Tip-Enhanced Raman Spectroscopy - Finds a Growing Number of Applications in Biology -

Auteur : Marc CHAIGNEAU*, Maruda SHANMUGASUNDARAM, Fran ADAR

2 février 2019


Figure 1 Reflection and transmission TERS configurations

Author(*) Infomation: HORIBA FRANCE SAS

Abstract: Tip-enhanced Raman spectroscopy (TERS) combines the high chemical specificity of Raman  scattering  with the nanoscale spatial resolution of Scanning Probe Microscopy (SPM). It enables label-free  detection of surface components in multi-component samples with ultra-high spatial resolution (better than  20 nm). This aarticle describes how TERS can be applied to study biological systems ranging from pure  components like amino acids to membrane receptors found in complex environments such as cell surfaces.

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