Explore all questions and answers from the workshop. If you need any further questions or additional information, feel free to contact us.
The temperature is measured inside the instrument during each analysis. It is recorded in the raw data for the calculation of the ESR result. This is a specific correction calculation, different from that used for sedimentation rate.
Not exactly at the same time, because to perform ESR + DIFF, you need two different samples. The advantage is that ESR measurement, done independently of the blood count, ensures it doesn’t interfere with the device’s other functions.
ESR = 1 test = 1 sample (180µL)
DIFF = 1 test = 1 sample (20µL)
Reminder: It is possible to update a Yumizen H550 (H500) V3 to V4, but without the ESR version.
There is a flag on the main screen report and a value in the Expert mode screen. There is no Rheo-D curve. It is a time measurement that triggers the “poikilocytosis” symptom above 0.5 seconds.
NB: In the Expert mode screen, you also have an ESR result with 0.1 millimeters precision. This precision is relevant for very low ESR.
The main difference is that ALIFAX does not use a diluent, meaning the blank measurement is done on an empty tube. This means the ESR value depends on the luminosity. The luminosity of LEDs is not stable; it changes with age and temperature. Therefore, it’s not a direct luminosity measurement but a transformation to Beer-Lambert optical density by the blank measurement, which is done with the diluent in our instrument. This makes the measurement more accurate.
There are no significant limitations yet, except for very high ESR values. The dynamics of raw measurements decrease with high ESR, meaning we are not precise at high values. However, up to 120 mm, which is already pathological, performances are validated and accurate. Very high values above 120 are rare and remain pathological, so this would not impact the diagnosis.
This may depend on the country or the clinician, but here is an example of a widely used recommendation (source):
Male <50 years old: ≤15 mm/hr
Female <50 years old: ≤20 mm/hr
Male >50 years old: ≤20 mm/hr
Female >50 years old: ≤30 mm/hr
Child: ≤10 mm/hr
Here is what is indicated in our user manual:
Parameter (Conventional Units) | 0 - 30 days | 1 - 6 months | 6 months - 2 years | 2 - 6 years |
ESR | 0 - 2 | 0 - 20 | 0 - 20 | 0 - 20 |
Parameter (Conventional Units) | 6 -12 years | 12 -15 years | 15 -18 years | 18 - 21 years | |
Female | Male | ||||
ESR | 0 - 2 | 0 - 20 | 0 - 20 | 0 - 20 | 0 - 15 |
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