How does the system work?

Our systems are based on prism-coupled SPR.

A collimated beam is sent towards the functionalized gold surface through the prism in order to illuminate the entire spotted matrix (there is no need to perform a 2D scan of the matrix).

After reflection on the chip, the beam is intercepted by a CCD array (2D matrix) where each pixel corresponds to a given location on the SPRi-Biochip.

HORIBA Scientific-Genoptics proprietary optical configuration enables a simple yet very precise imaging system without any moving part but a scanning mirror.

The rotation of this mirror allows the selection of the working angle relatively to the resonance angle for kinetic measurements. The working angle (position at which kinetic curves will be recorded) is chosen at the highest slope of the reflectivity curve.

Kinetic measurements consist in monitoring reflectivity variations against time simultaneously on up to several hundred spots.