SPRi-Biochip™ definition

SPRi Biochip

SPRi-Biochips™ are designed exclusively for the SPRi-Plex™ and SPRi-Lab+™ systems. The chips are made of a high refractive index glass prism coated with a thin gold film specially developed for imaging purposes. Importantly the Biochips can be provided with pre-functionalized Surface Chemistry or as bare biochips suitable for exploring your own chemistry and target molecule detection.

To detect biomolecular interactions, probes are first grafted (spotted) onto the chip surface. Depending on the diameter of the spots, up to 400 spots (200µm) or 64 spots (500µm) can be deposited on the 1cm2 sensitive surface of the biochip.

With the appropriate regeneration procedure, spotted SPRi-Biochips™ are re-usable at least 30 times. [ref:Cherif B. and al.]saving on consumable costs.

Spotting can be performed and developed according to your own requirements or we also offer the possibility of performing electrodeposition with a SPRi-Spot™ manual spotter or, for more demanding applications, with some commercially available microarrayers through the addition of an electrodeposition module.