Megakaryocyte

Very large size cells visible at low magnification with MGG on bone marrow smears.

Shape: variable, maily globular

Nucleus: polilobed, varuiable shape

Chromatine: dense

Nucleolus: absent

Cytoplasm: abundant, acidophil, numerous granulations, platelet release in blood vessels

Thrombocytogenous megakaryocytes can be observed  with nucleus becoming dense.