SPRi - OpenPleX

OpenPleX

Manual label-free molecular interaction analysis machine Flexible Research Platform

Surface Plasmon Resonance imaging made easy

Designed to meet the demands of biologists, biochemists and biophysicists, the OpenPlex is a flexible surface plasmon resonance imaging system.
OpenPlex is your companion for the development of label-free and multiplexed bio-assays and molecule detection. It is a robust and compact system designed for simple use and high versatility. Its open format, dedicated sensor chips and manual operation enable numerous types of experiments to be explored without compromise, covering chemistry, biochemistry, physico-chemistry and biomolecular interactions.

Open your research areas with OpenPlex! Choose between three different flow cell configurations without concession:

  • Normal flow cell for standard surface plasmon resonance imaging experiments
  • Window flow cell, compatible with fluorescence measurements
  • Cuvette cell, compatible with electrochemistry measurements
Segment: Scientific
Division: Molecular and Microanalysis
Base product
Manufacturing Company: HORIBA France SAS

Manual and flexible Surface Plasmon Resonance imaging system for:

  • Label-free interaction analysis
  • Real-time monitoring of kinetic curves
  • Determination of affinity/kinetic parameters
  • Multiplexed imaging (up to 400 spots)
  • NEW: Temperature control: 15 - 40 °C

 

Testimonials

Dr G. Penner OpenPleX testimony 

"We are able to generate consistent results that enable us to identify full binding coefficients for multiple candidate aptamer sequences simultaneously. The instrument […] has become one of the most essential tools that we have." Dr. G. Penner, NeoVentures Biotechnologies, Canada

Prof. Maryam Tabrizian OpenPleX Testimony 

"…an essential tool […] for the characterization of sophisticated ultrasensitive diagnostic platforms integrated with either nanomaterials, modified gold nanostructures or microfluidics”
Prof. Maryam Tabrizian, McGill University, Canada

DR E. Goluch, OpenPleX testimony 

“The accessibility of the hardware and the flexibility of the software […] allow us to stretch the limits of what can be studied with SPRi. We have been able to modify the flow cell to study bacterial cells and biofilms in unique geometries.”
Dr. E. D. Goluch, Northeastern University, USA

 

  • Sample volume: typically 200 μL
  • Sample concentration: 300 ng/mL (100-1000 kDa) to 10 μg/mL (4-20 kDa)
  • Sample molecular weight: > 240 Da
  • Limit of detection: 10 pg/mm2
Antibody-Antigen Specific interaction
Antibody-Antigen Specific interaction
Interaction between immobilized peptides and protein from sera on Cystamine / Glutaraldehyde functionalized biochip
Interaction between immobilized peptides and protein from sera on Cystamine / Glutaraldehyde functionalized biochip
Protein-Peptide interactions studies with SPRi
Protein-Peptide interactions studies with SPRi
Description of the advantages of combining the use of peptide chips with direct label-free detection as achieved by SPR imaging (SPRi).
SPRi Imaging of oligosaccharides proteins interactions
SPRi Imaging of oligosaccharides proteins interactions
Real time detection of lymphocytes with SPRi
Real time detection of lymphocytes with SPRi
The Detection of a Low Molecular Weight Enzyme Inhibitor using the OpenPlex™ system
The Detection of a Low Molecular Weight Enzyme Inhibitor using the OpenPlex™ system
OpenPlex Brochure
CategoryDocuments
Size 3.26 MB
FiletypePDF

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Product accessories

OpenPlex Software Suite
MoreOpenPlex Software Suite
SPRi software suite for simple use and easy data analysis.
Reagents for label-free interaction analysis
MoreReagents for label-free interaction analysis
Sensor Chips for Label-Free Interaction Analysis
MoreSensor Chips for Label-Free Interaction Analysis
SPRi-Arrayer
MoreSPRi-Arrayer
Direct contact spotting
SPRi-Continuous Flow Microspotter™ (SPRi-CFM)
MoreSPRi-Continuous Flow Microspotter™ (SPRi-CFM)
Automatic printer for biomolecules

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