Total Organic Carbon Monitor

The continuous online TOC-Analyzer HT-110 is suitable for the measurement ot total organic carbons in Purified Water (PW), Water For Injection (WFI) and Highly Purified Water (HPW). The unit is operating according to USP 643. It is applicable for pharmaceutical and/or semiconductor manufacturing. The measuring principle is based on UV-Oxidation and measurement of the difference in conductivity. TOC concentration measurement (TOC concentration 500 ppbC or lower) is necessary to perform quality control according to GMP (Good Manufacturing Practice).


Division: Process Water
Manufacturing Company: HORIBA Advanced Techno Co., Ltd.


  • UV-Oxidation and conductivity determination: This method eliminates the need for reagents and carrier gases. It delivers an accurate measurement at low concentrations, like for instance in WFI (Water For Injection) areas and reduces the cost of operation at the same time.
  • “Debubbler“ embedded: Bubbles in production systems often cause unstable readings in many instruments. The embedded “Debubbler“ eliminates the influence of air and guarantees a stable measurement.
  • Optional external ON/OFF control of contact input terminals.
  • Maintenance cycle: “ONLY ONCE PER YEAR“: Maintenance only consists of annual UV-lamp exchange and annual calibration.
  • Conforms to: United States Pharmacopeia: USP <643>.
  • Reference solutions for System Suitability Test (SST): 1,4 Benzoquinone and Sucrose
  • Choice of 3 installation methods: Possible to install on a pole, wall or desktop.



Product nameTotal organic carbon analyzer (TOC analyzer)
Measurement methodContinuous UV oxidation conductivity method
Measurement limit0 ppb to 1000 ppb
Measurement range0 ppb to 100/500/1000 ppb
RepeatabilityWithin ±2% of full scale
Display resolution0.1 ppb (0 ppb to 100 ppb/0 ppb to 500 ppb range)
1 ppb (0 ppb to 1000 ppb range)
Transmission outputNumber of output point: one
4 mA to 20 mA DC/0 V to 1 V DC (optional) insulated input/output
Maximum load resistance: 600 Ω (minimum load resistance 100 kΩ (when optionally selected))
Transmission output range: optional setting possible within measurement range
Output target: TOC concentration
Contact outputNumber of outputs: 2
Alarm contact output (RLY1)
Contact method: relay contact, SPDT (1c)
Contact capacity: 125 V 3 A AC/24 V 3 A DC (load resistance)
Contact function: upper/lower limit function (ON/OFF control)
Output target:
at TOC, temperature, conductivity:
C-NO contact is “closed” during operation, “open” during normal conditions
(including a POWER OFF state) *C-NO contact is reversed at hold, or error:
C-NO contact is “open” during operation (including a POWER OFF state),
“closed” during normal conditions *C-NO contact is reversed
Alarm contact output (RLY2)
Contact method: relay contact, SPST (1a)
Contact capacity: 125 V 3 A AC/24 V 3 A DC (load resistance)
Contact function: upper/lower limit function (ON/OFF control)
Output target: TOC concentration
Contact inputNumber of input point: 1
Non-voltage normal open (1a) signal input (open collector input possible)
Insulation-type input
Max. ON resistance: 50 Ω
Open-circuit voltage: 5 V DC
Max. short circuit current: 10 mA
An error will not be generated even if there is notification of no sample detection
immediately after receipt of the pure water device stop signal receiving
The hold operation during the contact input receiving.
Sample water conditionConductivity: less than 10 μS/cm (less than 2 μS/cm in 0 ppb to 100 ppb range)
Temperature: 5℃ to 99℃
Pressure: 0.03 MPa to 0.50 MPa,
Pressure fluctuation: within ±0.05 MPa (within the specified pressure range)
Flow rate: 20 mL/min to 200 mL/min
Environmental conditionsTemperature: 5℃ to 40℃
Relative humidity: less than 85%
InstallationInstall place: indoor
Display functionLCD (with a back light) TOC, conductivity, water temperature, alarm
Power100 V to 240 V AC ±10%, 50 Hz/60 Hz built-in fuse 250 V AC 3.15 A (T)
Power consumption80 VA (max.)
Outside dimension300 (W) × 400 (H) × 165 (D) mm
Mass13 kg
Concerned directivesCE markingEMC Directive: EN61326-2-3
Low Voltage Directive: EN61010-1
RoHS Directive: EN50581
FCC RuleFCC parts 15
Protection structureIP 43 (IEC60529, JIS C0920)
Pollution level 2 (IEC61010-1)

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