Large size cell, concave nucleus (isthmus> 1/3 of the nucleus size), quite dense chromatin, pale basophilic or neutrophilic cytoplasm, many neutrophilic granules, no visible Golgi apparatus.
Presence in the blood = Myelemia.
Hematologic Diseases: Chronic Myeloid Leukemia + + +, Primary Myelofibrosis (erythromyelemia)
Reactive etiology: Severe Infection, Granulocytic Regeneration, Treatment with G-CSF.