Applications

Noninvasive In-Vivo Determination of Sunscreen-UVA Protection Factors

Noninvasive In-Vivo Determination of Sunscreen-UVA Protection Factors

Noninvasive In-Vivo Determination of Sunscreen-UVA Protection Factors

The development and evaluation of UVA (320–400 nm) sunscreens is important because UVA sunlight can penetrate deep into human skin and cause severe internal damage, as well as erythema and photoaging. Human phototesting is usually used for determining the sunscreen protection factor (SPF), defined as the ability of a sunscreen to prevent a threshold erythema from solar radiation. The SPF definition is now considered as the tentative final FDA standard for measuring SPF. The SPF measured with this method, however, results primarily from UVB (280–320 nm) and not from UVA. Phototesting is unsuitable for the evaluation of UVA protection factors (PFA) because of the extremely long exposure time necessary to generate erythema from UVA radiation and the concerns of reciprocity. Recently, several in vivo and in vitro methods using animals have been proposed. However, none of the methods is capable of measuring the efficacy of UVA sunscreens in vivo on human skin.

Application Downloads

Related Products

제품 문의

HORIBA제품의 자세한 정보를 원하시면, 아래의 양식에 내용을 입력을 부탁드립니다.

* 는 필수입력항목입니다.

Corporate