What is the difference with channel systems?

In channel systems, it is possible to monitor only a few interactions in parallel. Imaging systems enable up to several hundred interactions to be monitored in parallel.

The number of channels corresponds to the number of different ligands that you can immobilize. The ligands are immobilized in the system, using the micro-fluidics system. Microfluidics requires less sample volume but has limitations for some applications (serum, plasma, cells…).

Also, the coupling with other techniques, such as mass spectrometry is difficult with channel systems. In fact, the sample must be recovered and re-concentrated several times, increasing experimental steps, risks for sample contamination and sample loss. HORIBA Scientific-GenOptics instruments make SPRi-MS fast and straightforward.

Multiplex format

Channel format

  • 16 interactions in real-time
  • 4 different molecules
  • 4 different concentrations for each
  • 4 different negative controls at 4 concentrations
  • On the same biochip
  • 3 interactions in real-time
  • 3 different molecules
  • 1 concentration for each
  • 1 negative control
  • For 16 interactions -› 6 biochips

Working with multiplex can save 3 months work