SPR-MS coupling: The SuPRa-MS platform

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Direct SPR-MS analysis on a single biochip

Fully characterize your interactions using SPRi coupled to Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) while increasing your candidate throughput for applications like ligand fishing.

In collaboration with the CLIPP proteomic platform, we offer you the opportunity to identify and quantify many spatially resolved samples in a multiplex format.

The SuPRa-MS platform
  • Label-free detection of biomolecular interactions
  • Multiplexed binding characterization
  • Simple transfer of the SPRi micro-array biochip to MS (no elution step)
  • Direct MS and MS/MS analysis on the SPRi micro-array biochip

MS analysis is directly performed on the SPRi biochip thanks to our compatible proprietary surface chemistry (developed with LAMBE, UMR 8587 CNRS). The CS surface chemistry avoids non-specific binding on the surface of the biochip and facilitates subsequent MS analysis.