January 2024
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Patient Demography: Man, 73 years old
Diagnosis: Myelofibrosis
Microscopic Review: Neutrophils: 76%, Metamyelocytes: 1%, Myelocytes: 7%, Promyelocytes: 1%
Other Information: Hemoglobin electrophoresis: HbA1: 94.5%, HbA2: 5%, Fetal Hemoglobin: 0.5%, Protein electrophoresis: PT: 7.5, A/G: 1.2 no monoclonal peak. Splenomegaly. DHL: 769, PCR: 18.8
How Yumizen Can Assist: On the RBC histogram, we observe anisopoikilocytosis. The Yumizen H2500 can give the number of microcyte cells: 66.5% of the total RBC population have a mean volume of 53.7 fl. The same can be seen in RBC morphology which shows microcytic red cells with dacryocytes and a few poikilocytic red cells. One of the features of myelofibrosis is seen as an increased RDW-CV of 25.6%. The WBC diff matrix shows a shift to the left as increased LIC value on WBC differential counts suggests immature WBC cells on a blood smear.
This clinical case has been provided by a Brazilian Consultant Pathologist.
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