Articles

The Yumizen H2500 (YH2500) cell analyser was compared to the Pentra DX Nexus (both from HORIBA Medical) to evaluate the efficiency of the new YH2500 technology for the WBC-differential in samples from oncology patients with WBC-diff abnormalities.

Explore reference ranges for PT, aPTT, and fibrinogen in dogs and cats using the Yumizen G200 analyzer—advancing veterinary diagnostics with reliable data.

This study investigates how Artificial Intelligence (AI) can be integrated into hematology workflows and revolutionize sepsis detection, using only Complete Blood Count (CBC) data obtained from Yumizen H 2500 and H1500 analyzers, in combination with the Generative Manifold Learning (GML) framework developed by GeodAIsics.

Improve oncology care with Yumizen H500—HORIBA’s rapid, near-patient blood testing solution for faster treatment decisions and better patient outcomes.

This study evaluates the performance of the HORIBA Yumizen H2500, along with its middleware Yumizen P8000, in identifying blasts, atypical lymphocytes, and immature granulocytes. Key diagnostic metrics such as sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), were analyzed to determine the diagnostic accuracy of the analyzer.

Explore the critical role of reticulocyte parameters in erythropoiesis and anemia monitoring, and learn how flow cytometric methods enhance precision and efficiency in measuring these vital indicators. This article provides insights into diagnosing anemia, assessing bone marrow activity, and monitoring iron deficiency for healthcare professionals and researchers.

The diabetes epidemic continues to grow worldwide. HbA1c testing may be implemented as part of the diagnostic, prognostic, and monitoring process, leading to better patient care and successful clinical outcomes. This article discusses the crucial role, testing methods, and accurate and efficient solutions for diabetes mellitus.

This article explores the HIL interference in hemostasis laboratory practice and how auto-check systems can enhance productivity and ensure quality results.

The article explains how the automated infectious flags in complete blood count can help screening of malaria and dengue infections in a clinical setting, in a cost-effective manner.

The Microsemi CRP from HORIBA Medical gives a Full Blood Count (FBC) and CRP result in 4 minutes from 18 uL of sample. FBC and CRP are good indicators for sepsis detection, differentiating bacterial from viral infection and can help reduce antibiotic prescribing to help in the battle of anti microbal resistance.

In cooperation with Kyoto Prefectural University of Medicine, the performance of the Banalyst HbA1c chip was evaluated (accuracy, repeatability, and correlation with HPLC).

HORIBA Medical, in collaboration with its customers Mick Chomyn and Martin Fottles from Path Links Pathology Service, has published a white paper on the application of LEAN principles to Healthcare entitled “TLA – the ‘LEAN’ Alternative”. Focusing on the elimination of waste, LEAN principles offer a variety of tools and techniques to achieve this aim. The white paper focuses on the practical application of these principles based on the experiences of this large UK hospital laboratory group.

The study compared the performance of two advanced hematology analyzers: Sysmex XN‐3000 and HORIBA Medical Yumizen H2500.

Immature granulocytes, a hematological biomarker, help to establish the severity of infection and risk of Sepsis for patients in the emergency department and those showing early signs of infection at physician's clinics. This article features their clinical significance, the measurement technology, and the HORIBA immature granulocyte parameter IMG on its Yumizen hematology analyzers.

The article explains the scientific evidence and technical aspects behind the presence and formation of large "young" platelets in various pathological conditions. It also emphasizes the medical value of using the Large Platelet Fraction parameter for the diagnosis and treatment of platelet-related disorders.

On PLTOx mode of Yumizen analyzers, two measuring methods, impedance and light extinction (absorbency), are combined in order to obtain the most reliable result.

On PLTOx mode of Yumizen analyzers, two measuring methods, impedance and light extinction (absorbency), are combined in order to obtain the most reliable result.

Atypical lymphocytes are lymphocytes that have been activated to respond to a viral infection (occasionally a bacterial or parasitic infection). Yumizen H1500/H2500 hematology analyzers provide the ALY parameter in percentage and absolute count.

The Double Hydrodynamic Sequential System (DHSS) technology is the technology from HORIBA Medical. Its significance is to ensure a linear flow of cells through electrical impedance method and optical measurement which helps in well differentiation of WBCs sub-population, along with Platelets. Double Hydrodynamic focusing is a technique used to provide accurate results from flow cytometer.

Yumizen H2500/H1500 hematology analyzers ensure perfect homogeneity of blood samples with its rack rotation module. Its rotary-type module is automatic and rotates 360 degrees, achieving optimal conditions for obtaining precise results.

In hematology analysis, Large Immature Cells parameter has been used to flag semples containing abnormal leukocytes. Compared to similar analyzers, Yumizen analyzers give food performance of 5-part leukocyte differential analysis and LICs, strongly correlated to microscopic cytology analysis.

Clinical chemistry is notoriously difficult to transfer out of the laboratory, but the emergency department at Newham University Hospital NHS Trust is leading the way in point-of-care testing and has improved patient waiting times in the process.

Meeting CPA requirements is a fundamental requirement for all POC tests, as it is essential to ensure that only trained personnel who understand the correct operation of remote analyzers are able to access them. Guaranteeing the quality of results that clinicians ultimately act upon is crucial to patient safety, while achieving compliance to CPA standards demonstrates confidence and a level of trust in the pathology services provided by hospitals, clinics and POC testing facilities.

Point-of-care testing may have been highlighted in Lord Carter’s report on pathology but this is nothing new to those providing an important service across three counties in south-east England. Here, Lynda Petley (Frimley Park NHS Foundation Hospital Trust and Royal Surrey County NHS Foundation Trust) provides a personal view of a trust-wide initiative.

Mick Chomyn and Martin Fottles from Path Links Pathology Service illustrate how Lean work cells deliver faster turnaround times, higher productivity and efficiency, increased flexibility, improved space utilisation, and quality.

The aim of this document is to show the biological markers involved in screening, triage and prognosis, which involves white blood cells, platelets, Ddimer, CRP and fibrinogen. While acknowledging that these parameters are not exhaustive, they nonetheless represent essential biological markers for the management of the COVID-19.

In partnership with the Christian Medical College (CMC) in Vellore, India, HORIBA Medical has adapted the world-renowned Overall Equipment Effectiveness (OEE) assessment method to the hematology field. This valuable new decision-making approach for laboratories has been published in the Practical Laboratory Medicine journal.

This study was designed to answer the question whether a graphical representation increase the diagnostic value of automated leucocyte counting of the synovial fluid in the diagnosis of periprosthetic joint infections (PJI).

This study evaluates the three methods of reticulocyte counting, namely automated, flow cytometry, and manual methods for reticulocyte count and also for the enumeration of immature reticulocyte fraction (IRF).

Automated hematology analyzers often generate many flags which can provide important clues to the underlying hematological abnormality. Although pathologists are generally well versed in recognizing the importance of flags indicating potential leukemic blasts, their utility in hinting toward infectious etiology, especially during epidemics, is less well known. We analyzed any abnormal flags generated by a three‑part automated hematology analyzer in serologically confirmed cases of dengue.

This study is meant to evaluate third party reagents in terms of quality and impact on patient results and impact on analyzer in comparison to reagents supplied by original equipment manufacturers.