No need to sample—simply take your readings directly in place in locations such as reaction vessels
Collecting samples during a continuous process can be tedious and even dangerous if hazardous materials are involved. In applications such as reaction monitoring, sampling can also be difficult to accomplish without interfering with the process being analyzed or altering the data. Sampling can change temperature and pressure conditions, or allow volatile components to evaporate, all leading to errors in the measurement. Furthermore, in vitro sample handling and measurement takes time and effort, meaning your data are always behind the actual state of the process.