Yumizen H500 CRP

Hematology Analyzer

A New Standard for Near-Patient and Hospital Testing

The Yumizen H500 CRP combines advanced hematology analysis with rapid CRP measurement in a single, compact unit. It performs simultaneous 5-part leukocyte differential (DIFF) and CRP testing using whole blood. Powered by i-DoubleDiff technology, it provides detailed insights into three immature white blood cell populations and includes screening flags for Malaria and Dengue infections. Its intuitive touchscreen interface ensures fast and user-friendly operation.

*This product may not be available in your country or region at this time. Please contact your HORIBA sales representative or distributor for more information.

Segment: Healthcare

Division: Hematology

Manufacturing Company: HORIBA ABX SAS

Base product: Yumizen H Range

Features
Specifications

Key Features

Simultaneous 5-part DIFF + CRP testing
Whole blood/capillary sampling (27 µL, closed tube)
Zero-maintenance design
i-DoubleDiff technology for extended WBC differentiation
Screening flags for Malaria and Dengue
Up to 60 hematology tests per hour
Multiple analysis modes: standard, prediluted, eQC, etc.
38-parameter menu including IML, IMM, IMG, ALY, and CRP
Bidirectional connectivity (ASTM and HL7)
New graphical interface with color-coded menus
Comprehensive QC management: iQC indicators, overlapping QC, repeatability testing
Yumicare remote assistance service

Clinical Benefits

The Yumizen H500 CRP enables:

Efficient and simplified patient triage
Targeted antimicrobial prescriptions
Monitoring of disease progression through dynamic parameter tracking
Reduced duration of antimicrobial treatments
Potential cost savings and shorter turnaround times (TAT)
Potential reduction in hospitalization duration

Diagnostic Capabilities

Complete RBC, hemoglobin, and platelet analysis for anemia and hematological disorders
Quantitative WBC analysis, including immature forms
Neutrophil and eosinophil counts for monitoring drug effects and asthma
CRP values for detecting inflammatory and infectious diseases
Optional screening flags for Malaria and Dengue

PHYSICAL SPECIFICATIONS
Dimensions & Weight	WDH (mm): 397(W) × 477(D) × 483(H) mm, 25.8kg
Printer (optional)	Compatible models with Linux drivers
Sample Management	Closed Tube/sample holder
Analysis Mode	CBC, DIFF CBC+CRP, DIFF+CRP, CRP
Sound Level	57 dBa
Operating Temperature & Humidity	Operating Temperature & Humidity: +18°C (64+°F) to + 30°C (+86°F) Relative humidity ~80%, without condensation
Specimen Type & Volume	Human venous and capillary blood Whole blood, serum or plasma from vein for CRP measurement EDTA K2, EDTA K3 anticoagulant CBC, DIFF: 20 μL CBC+CRP, DIFF+CRP, CRP: 27 μL
Power Requirements	Power Supply: AC 100-240V (within ±10%), 50/60Hz Power consumption: 190 VA Heat output: 378 KJ/h
Reagents	ABX Diluent (10L or 20L), Whitediff 1L (cyanide free), ABX Cleaner 1L, CRP UNIT50 (50 tests * 2 pcs), 1 reagent for concentrated cleaning: ABX Minoclair

ECO FRIENDLY SOLUTION

LED light source
Cyanide free lysis reagent
WEEE Standard compliance

MEASUREMENT PRINCIPLES
WBC & Differential
Methods	Cytometry : Double Hydrodynamic Sequential System ‘DHSS’ Optical Reading : Absorbance Impedance Variation
HGB Measurement Method	Spectrophotometry
RBC & PLT Detection Methods	Impedance Variation Analogic Digital Conversion
HCT Measurement Method	Analogical integration
CRP
Latex immunity turbidity rate method

PARAMETERS & PERFORMANCE DATA

38 Parameters

WBC NEU# NEU% LYM# LYM% MON# MON% EOS# EOS% BAS# BAS% IMG# IMG% IML# IML% IMM# IMM% ALY# ALY% LIC# LIC% RBC HGB HCT MCV MCH MCHC RDW-CV RDW-SD MIC MAC PLT MPV PCT PDW P-LCC P-LCR CRP

SOFTWARE SPECIFICATIONS

Data Processing

Color LCD touch screen: 12.1 inches
Operating System: Linux™
Connection: RS232, Ethernet, USB
Communication: ASTM & HL7 protocols
Capacity: 10 000 results + graphs
Options: keyboard, mouse and barcode reader

Quality Control

CBC/DIFF - 3 controls levels (Low, Normal, High)
CRP-2 levels (Low, High)

QC results compatible with HORIBA Quality Control Program (QCP), Levey-Jennings graphs, Radar graphs, XB on 3 or 9 parameters, Overlapping QC (DiFF - 6 active QC files)

ANALYTICAL MEASUREMENTS
Linearity	Linearity Limits	Visible Range	Unit
WBC	0-300	300-999	10⁹/L
RBC	0-8	8-18	10¹²/L
HGB	0.0-24.0	24.0-30.0	g/dL
HCT	0-67	67-80	%
PLT (HGB >1.5 g/dL)	0-2500	2500-4000	10⁹/L
PLT (HGB <1.5 g/dL)	0-4000	4000-5000	10⁹/L
CRP (HCT ≥23%)	0.0-200.0	200.0-230.0	mg/L
CRP (HCT <23%)	0.0-150.0	15.0-170.0	mg/L
Limit of quantitation	Value	Unit
WBC	0.2	10⁹/L
RBC	0.2	10¹²/L
HGB	1	g/dL
HCT	2	%
PLT	10	10⁹/L
CRP	1	mg/L
Precision	CV%	in Range	Unit
WBC	3	4-10	10⁹/L
RBC	2	3.6-6.2	10¹²/L
HGB	< 1.5	12.0-18.0	g/dL
HCT	< 2.0	36-54	%
PLT	< 5.0	180-500	10⁹/L
CRP	< 10.0	0-10.0	mg/L
CRP	< 8.0	10-120.0	mg/L