AFM Optical Platform

Designed to be combined with Optical Spectroscopies

The AFM platform allows fully-integrated use of confocal Raman microscopy and AFM for Tip-Enhanced Optical Spectroscopies (such as Tip-Enhanced Raman Spectroscopy (TERS) and Tip-Enhanced PhotoLuminescence (TEPL)), but also for truly co-localized AFM-Raman measurements.

The myriad of AFM (Atomic Force Microscope) techniques that allow study of topographical, electrical and mechanical properties can be performed with any laser source available in Raman spectrometer, or with other external illumination (e.g., solar simulator or other tunable or continuum source). TERS and TEPL can provide nanoscale chemical and structural information, making the AFM-Raman platform a two-way road; where complimentary techniques provide novel and unique imaging capabilities to each other.

AFM-Raman presentation

Nano Spectroscopy Solutions with AFM-Raman, TERS, NSOM

HORIBA's leading Raman technology is now integrated with Atomic Force Microscopy (AFM). The end result is a more comprehensive sample characterization in one versatile instrument, for fast simultaneous co-localized AFM-Raman measurements, Tip-Enhanced Raman Spectroscopy (TERS) and Tip-Enhanced PhotoLuminescence (TEPL).

NanoRaman Webinar

Correlated Tip-Enhanced Optical Spectroscopy and SPM

We present in this webinar new nano-imaging capabilities. Tip-Enhanced Optical Spectroscopies (TEOS) such as TERS (Tip-Enhanced Raman Spectroscopy) and TEPL (Tip-Enhanced PhotoLuminescence) provide a unique capability for the characterization of molecules, 1D and 2D materials, semiconducting nanostructures and bio-materials.

Technology & F.A.Q.

AFM-Raman (co-localized measurements & TERS)

TERS brings Raman Spectroscopy into nanoscale resolution imaging. Learn more about this super-resolution chemical imaging technique.



“(…) Thanks to the customer-oriented culture of HORIBA, the nano-Raman team of LPICM is currently updating its “historical” prototype with the novel TERS system. It will allow us (…) to initiate new research areas, impossible to address with the present system.”
Prof. Razvigor OSSIKOVSKI, nano-Raman team leader, LPICM, Ecole Polytechnique, France

User's papers

Access a list of AFM-Raman user's publications and discover how TERS & TEPL create a high scientific impact.


AFM-Raman Trainings

Our trainers are experts in AFM-Raman technique. They will provide trainings advice and guidance to make the most of your HORIBA Scientific instrument. You will gain confidence and experience in the analysis of your samples.



TERS Characterization of Single- to Few-Layer Ti₃C₂Tₓ MXene

TERS Characterization of Single- to Few-Layer Ti₃C₂Tₓ MXene

Nanoscale chemical imaging of Single- to Few-Layer Ti₃C₂Tₓ MXene

MXenes is the largest and fastest growing 2D materials. They have unique properties such as good conductivity and a hydrophilic surface. The control of nanoscale composition would ultimately allow for engineering properties locally, gaining more control over the 2D material-based systems.

Read more
TERS on Functionalized Gold Nanostructures for Nano-scale Biosensing

TERS on Functionalized Gold Nanostructures for Nano-scale Biosensing

TERS Nano-localization of SERS hot spots

Surface-enhanced Raman scattering (SERS) is a powerful plasmonics-based analytical technique for biosensing. SERS effect relies on nanostructures that need to be designed to maximize enhancement factors and molecular specificity. In addition to numerical modeling, an analytical tool capable of imaging localized enhancement would be an added value.

Read more

RamanFest 2022

The International Conference on Advanced Applied Raman Spectroscopy (RamanFest2022) will feature presentations from world-leading Raman experts and researchers using the technique across varied applications within life science, materials science, and energy and environmental analysis. It will bring together the world's Raman community to share, learn and discuss how Raman spectroscopy is being applied to today's problems and pioneering tomorrow's capabilities.

Official website
TERS Characterization of phospholipid bilayers and detection of nanoparticles

TERS Characterization of phospholipid bilayers and detection of nanoparticles

Non-destructive and label-free hyperspectral chemical imaging of phospholipid bilayers with spatial resolution of 7 nm

Phospholipid bilayers, major constituents of membranes act as a barrier of selective permeability for the nanoparticles now largely into our environment. Studying the interactions between nanoparticles and cellular membranes requires a molecular chemical probe with nanometer resolution capability.

Read more
TERS Characterization of Graphene Nanoribbons

TERS Characterization of Graphene Nanoribbons

Graphene is foreseen for a handful of electronic and optoelectronic nano-devices. Making nano-devices out of graphene requires nanopatterning. Determining the quality of patterned graphene is essential and the detection of defects demands a sensitive chemical nano-characterization tool.

Read more

Webinar - Raman Spectroscopy, SERS and TERS Exploration of MXenes

Hear three experts in the field of Raman Spectroscopy discuss Raman, SERS and TERS for 2D materials.

Read more

TERS Characterization of Explosive Nanoparticles

It is not yet understood how co-crystal nanoparticles (co-crystallinity combined with nanostructuring) have superior properties to single compound crystals. Only a technique capable of probing single nanoparticles can bring answers.

Read more

c-AFM and in operando TERS & µRaman Characterization of Molecular Switching in Organic Memristors

Emergence of organic memristors has been hindered by poor reproducibility, endurance stability scalability and low switching speed. Knowing the primary driving mechanism at the molecular scale will be the key to improve the robustness and reliability of such organic based devices.

Read more
Correlated TERS and KPFM of Graphene Oxide Flakes

Correlated TERS and KPFM of Graphene Oxide Flakes

AFM-Raman and its TERS mode are used to show nanoscale surface mapping of structural defects and chemical groups on graphene oxide (GO) flakes with 10 nm spatial resolution. TERS mapping is combined with Kelvin probe force microscopy measurements for simultaneous topographical, electronic and chemical imaging of GO surface. The multi-parameter measurement methodology proposed in this note extends the capability of TERS allowing a direct correlation of local chemical composition and physical properties at the nanoscale not only for 2D materials but for almost any sample surface.

Read more
AFM-TERS measurements in a liquid environment with side illumination/collection

AFM-TERS measurements in a liquid environment with side illumination/collection

This application note reveals the key instrumental details to succeed in TERS measurements in liquids using side illumination/collection geometry. Such capability aims at bringing breakthroughs in many applications such as heterogeneous catalysis, electrochemistry, cellular biology and biomaterials. In this note, nanoscale chemical imaging of graphene oxide flakes and carbon nanotubes immersed in water is demonstrated with a TERS resolution down to 20 nm along with true non-contact AFM images.

Read more
Characterization of Nanoparticles from Combustion Engine Emission using AFM-TERS

Characterization of Nanoparticles from Combustion Engine Emission using AFM-TERS

A new concern for human health is now raised by sub-23 nm particles emitted by on-road motor vehicles. Beyond measuring particle number and mass, it is also critical to determine the surface chemical composition of the nanoparticles to understand the potential reactivity with the environment.

Read more
Correlated TERS, TEPL and SPM Measurements of 2D Materials

Correlated TERS, TEPL and SPM Measurements of 2D Materials

This application note reports on nano-characterization of 2D transition metal dichalcogenides (TMDCs) materials which are considered of very high potential semiconductors for future nanosized electronic and optoelectronic devices. Scanning probe microscopy giving access to the critical topographic and electronic properties at the nanoscale is coupled to photoluminescence (PL) and Raman spectroscopies by means of plasmon enhancement to yield correlated electrical and chemical information down to the nanoscale.

Read more

Browse Products

LabRAM Nano
more LabRAM Nano

AFM-Raman for physical and chemical imaging

XploRA Nano
more XploRA Nano

AFM-Raman for Physical and Chemical imaging

LabRAM Soleil Nano
more LabRAM Soleil Nano

Real-time and Direct Correlative Nanoscopy

more OmegaScope

The AFM optical platform

more SmartSPM

Advanced stand-alone AFM

more TRIOS

Versatile AFM Optical Coupling

more CombiScope

AFM and inverted light microscopy

Request for Information

Do you have any questions or requests? Use this form to contact our specialists.