Clinical Case 20 - Lymphoproliferative syndrome

Patient demography: Male aged 64
Diagnosis: Lymphoproliferative syndrome
Microscopic review: Neutrophils 4%, Lymphocytes 92%. The majority of the cells are small with clumped chromatin and scant cytoplasm. Smudge cells seen (++), Prolymphocytes 2%, Monocytes 2%.
How Yumizen can assist: On the DIFF scattergram, we observe the presence of atypical lymphocytes and cell population moving towards immature lymphocytic cells hints for Lymphoproliferative disorder like CLL. On the Baso histogram, we observe large cells on the right of the curve which correspond to the abnormal form’s cells seen in CLL. On WBC differential count analysis, the ALY count is high (Normal range 0 to 2.5%).
Analyzer: Yumizen H2500/H1500
Case provided by: a laboratory in France