A-TEEM Direktor

Your Guide to Multivariate Analysis

A-TEEM Direktor Multivariate Analysis (MVA) is a cutting-edge software designed to streamline and simplify the analysis of fluorescence A-TEEM data. With its intuitive interface and guided workflow, A-TEEM Direktor empowers researchers and analysts to extract meaningful insights from their data.

It is a tool designed specifically for fluorescence A-TEEM™ data analysis. The guided workflow takes a user step-by-step through data import, visualization, variable selection, preprocessing, and modeling A-TEEM calibration data sets. Prediction tools facilitate the application of calibration models to predict class or concentration information from new sample data.

Drag and drop functionality and a graphically driven user interface help to make MVA for A-TEEM a better experience. For GMP labs, A-TEEM Direktor includes a full audit trail, PDF report generation, and user login authentication.

To try out A-TEEM Direktor multivariate analysis software, please contact your local HORIBA sales or service office to request a 30-day trial license!

Product Video

Key Benefits

  • Ease of Use: Benefit from a user-friendly interface and drag-and-drop functionality, making A-TEEM Direktor accessible to users of all levels.
  • Flexibility: While A-TEEM Direktor is optimized for A-TEEM data, it can also be used to analyze other data types and spectra.
  • Guided Workflow: Follow a step-by-step process for seamless data import, visualization, variable selection, preprocessing, modeling and prediction.
  • GMP Compliance: Ensure data integrity and regulatory compliance with built-in audit trails, PDF report generation, and login authentication.
  • Versatile Modeling: Choose from a range of multivariate models, including PARAFAC, PCA, PLSR, PLS-DA, and more, to suit your specific analysis needs.
  • Context-Sensitive Help: Extensive tool tips and help menus are integrated throughout the software for quick explanations and user guidance.

 

The Power of A-TEEM

A-TEEM Spectroscopy simultaneously captures absorbance, transmittance, and fluorescence excitation-emission matrix data, while correcting for the inner-filter effect on the fly. This produces a three-dimensional plot of the sample under study. All this is nondestructive and takes a matter of seconds to produce.

Traditional fluorescence adheres to Beer-Lambert linearity, meaning that fluorescence intensity is linear with concentration and absorbance. Fluorescence spectra (and EEMs) can change non-linearly due to high optical density/high concentration and inner-filter effects.

This means that traditional fluorescence of solutions can only be quantitative if concentrations of fluorescing species have low optical density. At higher concentrations, the use of the absorbance spectra to correct for inner-filter effects allows fluorescence A-TEEMs to be used quantitatively and reproducibly over a wider range of samples and concentrations. 

Where can A-TEEM Direktor for MVA modeling fit?

  • Feasibility: A-TEEM Direktor can be used to analyze a variety of data types and spectra in order to determine if A-TEEM spectroscopy can work for those samples.
  • Method Development: Testing and planning of acquisition parameters, calibration sets (what samples to include) and defining model parameters. Choose and develop a model type (PARAFAC, PCA, or PLS) based on goals determined in Feasibility.
  • Method Deployment: Applying the validated method to new incoming samples for prediction (of sample ID, classifications, and/or concentrations, etc.).
  • Method Validation: Follow the method with an independent set of samples to ensure the process produces consistent and reliable results.
  • Maintenance: Update models when new information is available, or sample parameters change (accommodates additional variability in methods).
  • Support: MVA troubleshooting in any of previous areas.

 

Why Use A-TEEM Direktor?

A-TEEM Direktor software lowers the effort and time required to get EEM and A-TEEM data into a multivariate analysis solution, and get answers from the data. Guided workflows enable a user to navigate data import, visualization, variable selection, pre-processing, modeling and prediction step-by-step in an order that’s sensible for 3-way data, and highlights modeling data in a way that gets answers more clearly from potentially complex data sets.

All algorithms used in A-TEEM Direktor are referenced and validated, meaning that the results can be trusted. As a bonus, A-TEEM Direktor enables working in a GMP environment by having software login authentication, a full audit trail, and protection of original data. 

FeatureMinimumRecommended
ProcessorIntel i5, i7, i9, and Xeon Intel i7 for most tasks
Intel i9 or Xeon for data
intensive applications
Operating SystemWindows 10 and later (64 bit)Windows 10 64-bit
Memory (RAM)8 GB16 GB
Graphics CardDirect 9Direct 9
Hard Disk Storage1 GB500 GB to 1TB
File SupportMultiple open source formats, proprietary formats, and HORIBA .dat files from A-TEEM instrumentation

 

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