May 2025 (PDF for print)
Patient Demography: Male, 81 years old
Diagnosis: Metastasized adenocarcinoma of the prostate with bone marrow infiltration
Other Information: Known case of prostate adenocarcinoma and essential thrombocythemia
Microscopic Review: Neutrophils 45%, Lymphocytes 35%, Monocytes 10%, Eosinophils 1%, Metamyelocytes 9%, Erythroblast (nRBC): 4/100 WBC (orthochromatic with dyserythropoietic features). Few dysplastic/atypical nucleated cells seen.
Other Test: Non-mutated JAK2, mutated CALR. Imaging (CT) showing lymph nodes and bone involvement.
How Yumizen Can Assist: On the DIFF scattergram, we observe the presence of immature cell population and a few atypical/dysplastic cells (high % of LIC & ALY) which are not well classifiable in WBC differential. The high percentage of LIC and NRBC (with normal WBC range) on Yumizen H2500 hematology analyzer, with shift to left, along with a few dysplastic/atypical nucleated cells seen in microscopy, should think of bone marrow infiltration in this case. The patient is already a known case of adenocarcinoma of prostate, with bone metastasis.
This clinical case has been provided by the Laboratory of Portuguese Public Hospital.
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