Fluorescence

Biopharma Fluorescence Spectroscopy Solutions

Accelerating the development of next-generation pharmaceuticals and biotherapeutics requires precise, reliable tracking of complex biomolecules and advanced delivery systems. HORIBA’s specialized fluorescence technologies optimize these workflows by delivering critical chemical and physical profiling directly within cell media cultivation and downstream processing phases. Utilizing our proprietary A-TEEM optical fingerprinting method for adeno-associated virus (AAV) characterization and rapid vaccine batch validation, HORIBA provides the high-sensitivity insights needed to streamline quality assurance protocols. From initial laboratory discovery through full-scale commercial manufacturing, our targeted fluorescence solutions ensure production consistency, reduce processing bottlenecks, and safeguard drug efficacy.

Biotechnology Biology | Lanthanide-Based Sensors | Pharma

Biotechnology Biology

Why use fluorescence in BIOLOGY and BIOMEDICAL research?  

  • Many molecules in living systems are fluorescent or can be made to fluoresce 
  • Fluorescence reports on a molecular scale to give physical information about biological systems 
  • Helps us to visualize and detect molecules in-vivo 
  •  Extremely sensitive to environmental changes (temp, pH) 
  • Sensitive to conformational (structural) changes 

 

Why choose HORIBA fluorescence in BIOLOGY & BIOMEDICAL research? 

  • Highest guaranteed sensitivity 
  • Smallest volume of samples 
  • Breadth of product offering 
  • Experience in protein and cellular biophysics 
  • Systems tailored to biological research 

Lanthanide-Based Sensors

What are LANTHANIDE BASED BIOSENSORS used for? 

  • Immunological assays 
  • Glucose monitoring 
  • Protein-drug interactions 
  • Protein-protein interactions 
  • Conformational (structure) changes 

 

Why use HORIBA fluorometers to characterize LANTHANIDE BASED BIOSENSORS? 

  • Highest guaranteed sensitivity 
  • Unique single shot phosphorescence detection with SSTD 
  • Extended NIR lifetime techniques (TCSPC and SSTD) 
  • High sensitivity 
  • Upconversion capabilities 

 

Pharma

Why use fluorescence in PHARMA 

  • Fluorescence reports on a molecular scale to give physical information about biological systems 
  • More sensitive than other spectroscopies (UV-Vis) 
  • Extremely sensitive to environmental changes 
  • Sensitive to structural changes 

 

Why use HORIBA fluorometers in PHARMA? 

  • High guaranteed sensitivity 
  • Smallest volume of samples 
  • Lowest concentration of samples

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