Particle Correlated Raman Spectroscopy: Unlocking the Full Picture of Particulates in Pharmaceuticals

Particulate matter in pharmaceutical liquids is a major quality and safety concern regulated by USP 788. While traditional methods such as light obscuration and microscopic particle counting effectively size and count particles, they offer limited insight into particle composition—making it difficult to pinpoint whether particulates are inherent, process‑related, or extrinsic.

Particle Correlated Raman Spectroscopy (PCRS) transforms particulate analysis by integrating high‑resolution imaging with Raman spectroscopy to deliver complete particle characterization. This automated workflow provides particle size, morphology, and chemical identity at the single‑particle level, giving scientists an efficient way to correlate physical and chemical attributes.

In this webinar, you’ll discover how PCRS opens new possibilities for particulate analysis in the context of USP 788 and how chemically resolved particle data can enhance contamination investigations, clarify particulate origins, and strengthen product quality strategies. Attendees will learn how PCRS elevates quality control and root‑cause analysis through truly complete particle characterization.

What You Will Learn:

1. What PCRS is and how it delivers size, shape, morphology, and chemical ID in one automated workflow.
2. How PCRS identifies and characterizes multiple particulate components within a single sample.
3. How PCRS complements USP 788 methods to detect and chemically identify particulates for contamination analysis.

Who Should Attend:

• Pharmaceutical scientists, QC teams, and contamination‑control professionals.
• Analytical chemists working with Raman spectroscopy or particle imaging.
• Process development, manufacturing staff, lab managers, and technical leads.
• Formulation, inspection, and regulatory professionals seeking to link physical and chemical particle data or learn more about PCRS.

Speakers:

• Michelle Sestak, Ph.D. | Applications Scientist II
• Fiona Xi Xu, Ph.D. | Life Science Applications Scientist