Paris, France – August 06, 2025
Introduction
HORIBA is proud to announce the release of the RZ-660 In Vivo Raman Analyzer, a benchtop instrument designed for real-time, non-invasive molecular analysis of skin and biological tissues. This system is targeted at cosmetic developers, dermatologists, and researchers seeking precise skin characterization without the need for sampling.
Product Overview
The RZ-660 employs a 660 nm laser in a Class 2 safety rating to ensure user safety while providing high-quality skin insights. Its fiber-coupled probe, mounted on an articulated arm, enables easy positioning for vivo studies. The instrument integrates software for guided data acquisition and quantitative analysis, making it accessible for a wide range of applications.
Key Applications
- Assessment of skin barrier integrity and stratum corneum thickness
- Tracking of active ingredient penetration in topical formulations
- Monitoring skin hydration and lipid content changes
- Evaluating photoaging and sunscreen efficacy
Research Applications
- Mapping skin barrier function and hydration profiles
- Investigating lipid phase conformations and skin physiology
- Monitoring penetration kinetics of pharmacological or cosmetic agents of active ingredients
- Assessing inflammatory or photoaging effects on skin biochemistry and diagnosis
Design and Use Cases
The instrument is designed for benchtop use in clinical research labs, contract Clinical Research Organizations (CROs), and academic institutions. Its user-friendly interface and hands-free acquisition capabilities facilitate complex in vivo studies with reproducible results.
Technical Highlights
- Compact and portable design (< 25 kg) for laboratory settings
- Laser power: 18–19 mW at 660 nm wavelength
- Depth profiling (up to 200 μm) with less than 5μm of axial resolution
- Intuitive & easy to use software
More information
For more information, visit HORIBA’s website at: RZ-660 In Vivo Raman Analyzer
About HORIBA
HORIBA is a global leader in analytical and measurement technologies, delivering cutting-edge instruments and systems across a wide range of industries, including automotive R&D, environmental monitoring, semiconductor manufacturing, and scientific research. In the field of Life Sciences, HORIBA partners closely with customers to develop and deliver innovative analytical and automation solutions. Leveraging expertise in optical, electrochemical, and X-ray technologies, combined with advanced capabilities in sampling, engineering, and data science, HORIBA supports breakthroughs in drug development and manufacturing. Its mission is to drive the adoption of next-generation technologies and contribute to a healthier, more accessible, and more equitable healthcare system for all. Known worldwide for the quality and reliability of its products, HORIBA continues to empower scientific and medical progress through precision and partnership.
Press Contact
Laurence Boccard
Laurence.boccard(at)horiba.com
+33 (0)6 82711452
