Applications

Skin biomarkers and depth profile: PCA and PARAFAC correlations from HORIBA RZ‑660 skin probe analyzer

Skin biomarkers & depth profile: PCA and PARAFAC correlations from HORIBA RZ‑660 skin probe analyzer

Skin biomarkers identified by Raman Spectroscopy

With increasing regulatory requirements in cosmetics and dermo-cosmetics, non-invasive and reliable methods are essential to characterize interactions between products and skin biomarkers. Raman spectroscopy offers a unique solution as a non-destructive, non-contact, and rapid technique capable of probing molecular composition and depth profiles in vivo. Its high specificity allows differentiation of skin conditions through molecular fingerprints. When combined with advanced chemometric tools such as Principal Component Analysis (PCA) and Parallel Factor Analysis (PARAFAC), Raman data can be simplified and interpreted efficiently, enabling the identification and quantification of overlapping components. This approach provides robust, fast, and reproducible results, making Raman spectroscopy a valuable tool for clinical studies and regulatory compliance.

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Related Products

RZ-660
RZ-660

In Vivo Raman Analyzer

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