Biotechnology

What is Biotechnology?

Biotechnology is a major branch of life sciences that focuses on manipulating living organism and biological systems with the intent to create or modify products for specific use. Biotechnology uses a broad range of biology discipline such as genetics, biochemistry, molecular biology and so on. Biotechnology is used across a diversified range of applications, including medicine, agriculture, industrial, and environmental.

HORIBA offers a large choice of innovative technologies such as steady state and lifetime fluorescence, X-Ray fluorescence, particle size analysis and Zeta potential analysis to support a wide range of biotechnology applications.

Browse Applications

Production of a single domain antibody Q17c directed against recombinant HER2 protein and its binding study by Surface Plasmon Resonance imaging technology
Production of a single domain antibody Q17c directed against recombinant HER2 protein and its binding study by Surface Plasmon Resonance imaging technology
This application note shows how binding kinetics of single-domain antibodies can be studied with SPRi technology. QVQ produces single-domain antibodies from camelids (sdAbs or VHH). Like conventional Abs, sdAbs are able to bind specific epitopes with high binding affinity. The small size of sdAbs allows for enhanced tumor penetration and fast blood clearance, features that are favorable for in vivo imaging applications. Here, the binding of the anti-HER2 sdAb Q17c to recombinant HER2 protein was assessed using Surface Plasmon Resonance imaging (SPRi). An optimization of immobilization conditions was performed for Q17c and its specific antigen HER2 using a single SPRi-Biochip.
High Throughput Screening of Affimer Proteins using SPRi Label-Free Technology
Monitoring Whole Leaf Fluorescence Using Time‐resolved Techniques
Light incident on a leaf can be absorbed by chlorophyll to commence the photosynthetic cycle. Excess energy can be liberated as heat or by emission of fluorescence and this can be used to assess the efficiency of the photosynthetic process.
Stopped flow time‐resolved fluorescence study of serum albumin – curcuminoid binding
Rapid mixing accessories to perform stopped flow measurements have found application in characterizing interactions and reactions occurring in solution. Reactants are expelled from syringes, mixed and injected into a flowcell.
Dye‐protein binding monitored in a microliter volume using timeresolved fluorescence
The potential health benefits stemming from the antioxidant activity of curcumin, commonly found in turmeric (Curcuma longa L), has attracted the interest of several research groups.
Analytical Chemistry in Biotechnology

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TPNA-500
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Automatic COD Monitor

LAQUA PH1300
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LAQUAtwin pH-33
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LAQUAtwin pH-22
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LAQUAact EC220
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LAQUA EC1100
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XGT-9000
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X-ray Analytical Microscope

LAQUA PC1100
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LAQUAtwin K-11
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LAQUA DS-72
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LAQUAtwin Na-11
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LAQUAtwin Salt-22
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LAQUA F-73
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LAQUAact PH130
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LAQUAtwin Salt-11
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LAQUA F-72
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LAQUAact PH120
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LAQUAact PH110
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ICP-NEO Software HORIBA
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XGT-7200
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X-ray Analytical Microscope

SPRi Arrayer
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Direct contact spotting

Ultima
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Ultra Fast TCSPC Lifetime Fluorometer

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LED Phosphorescence Light Sources

OpenPleX
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Manual label-free molecular interaction analysis machine Flexible Research Platform

XelPleX
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Fully automated label-free molecular interaction analysis machine One System for Molecule Screening & Crude Sample Analysis

DeltaTime
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TCSPC Lifetime Kit

DeltaPro
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TCSPC Lifetime Fluorometer

DeltaFlex
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TCSPC Lifetime Fluorometer

XploRA INV
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Inverted Raman Microscope

Aqualog
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Water Treatment Plant Analyzer

HE-300C
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Industrial electric conductivity meter (Two-Wire Transmitter)

HP-300
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HE-200C
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HP-200
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Industrial pH meter (Four-Wire Analyzer)

HE-480C
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Industrial conductivity meter (low concentration type)

HP-480TP
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Industrial pH meter - Industrial time sharing proportional control

HC-200NH
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Ammonia Nitrogen Meter

HD-200FL
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Industrial dissolved oxygen analyzer (Four-Wire Analyzer)

HU-200SS
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Industrial MLSS meter (Four-Wire Analyzer)

HD-300
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Industrial dissolved oxygen analyzer (Two-Wire Transmitter)

HD-200
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Industrial dissolved oxygen analyzer (Four-Wire Analyzer)

HO-200
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Industrial ORP meter (Four-Wire Analyzer)

HE-960HI
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Sanitary Conductivity Meter (Wide-range type)

HD-480
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Industrial dissolved oxygen analyzer (The Slim48 series)

HE-960CW
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2-channel Sanitary Conductivity Meter (Low Concentration type)

HE-480H
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Industrial conductivity meter (high concentration type)

HE-300R
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Industrial electric resistivity meter (Two-Wire Transmitter)

HT-110
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Pharmaceutical Total Organic Carbon Monitor - Online TOC-Analyzer

HE-960RW
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Industrial resistivity meter

Sanitary Conductivity Sensor (Ferrule Clamp type) FES-210L
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Insertion sensor type for wide-range conductivity meter HE-960HI

FES-310L
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Sanitary Conductivity Sensor (Flow Through type)

ESH-01-C-SN
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Sanitary Conductivity Sensor (Ferrule Clamp type) for Low Concentrations

FS-01FC-SL Series
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Sanitary Conductivity Sensor (Flow Through type) for Low Concentrations