Biological applications of XRF microscopy

The effect of zinc on gastric ulcer healing has been investigated - mapped imaging of tissue samples shows evidence of zinc accumulation within the ulcerated tissue. In a separate study a fish otolith ('ear bone') has been analysed to reveal its heterogeneous elemental composition and physical structure.

(Left) Transmitted x-ray image and (right) zinc XRF intensity image of ulcerated rat stomach without medication. The ulcer region is circled.

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X-ray Analytical Microscope