Judicious Use of Antibiotics for Pediatric Infection

By: Kazunobu OUCHI

3 January 2016

— Global Strategies to Prevent the Increase of Bacterial Resistance—

Principle of antimicrobial therapy in children is to select and use the most appropriate antibiotics based on the inferred causative agent and with consideration given to the special characteristics of children. Resistant organisms have been increasing in recent years, so it is very important to use proper antibiotics based on a knowledge of antimicrobial susceptibility trends and Pharmacokinetics/Pharmacodynamics (PK/PD). We are careful to use antibiotics based on proper differential diagnosis using rapid diagnostic methods, Complete blood flow (CBC), C-reactive protein (CRP) and so on. The most practical means of judicious antibiotic use is to treat each patient based on the newly revised guidelines. As it is unlikely that many new antimicrobial agents will be developed in the future, we must maximize the efficacy and life span of current antimicrobial agents through judicious use.

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