Applications

化妆品

Characterization of cosmetic products

具有感知效果的创新化妆品的创造依赖于皮肤和头发基质的深刻科学知识,高效和安全的活性成分的开发,优化的配方和性能的仪器评估。从乳液、颜料或填料的粒径表征,到头发化学、表面功能化或摩擦学的分子分析,到配方稳定性、扩散或与包装的相互作用的评估,到污染或纳米毒性研究,从内源性皮肤化合物的体内评估到局部活性物质的渗透,HORIBA的仪器覆盖了化妆品和个人护理行业的大量应用。

How to improve cosmetic products?

Thorough characterization of ingredients, formulations, and products for safety, efficacy, stability, and regulatory compliance

HORIBA Solutions

Our solutions are tailored to provide valuable information on skin and hair helping to make informed decisions about cosmetic products

Application Notes

Browse our application notes to learn how our instruments enable comprehensive investigation of cosmetic products

FAQ

Explore our FAQs dedicated to advanced analytical solutions for comprehensive cosmetic products characterization

Users' papers

Discover how our instruments help research teams in solving their development problematics
 

Downloads

Download our brochure and eBook to find out about our full product and solutions offerings
 

How to improve cosmetic products?

Evaluating the impact of skincare products on the skin is crucial for assessing their effectiveness, ensuring safety, and enabling targeted delivery. This evaluation requires a good understanding of skin structure, and contributes to the overall well-being of individuals. In addition to the skin, there is a need for a deeper understanding of the structural and compositional changes that occur in hair under different circumstances. Prior to the evaluation step, the properties of raw materials should be carefully characterized, and their formulation optimized to ensure that they meet the highest standards of safety and quality.
HORIBA’s instruments can help with all these aspects to improve the performance of your cosmetic products.

In-vivo and ex-vivo evaluation

(Raman, Fluorescence)

  • Endogenous markers:
        Water, lipids, proteins, natural moisturizing factors
        Tryptophan, porphyrin, collagen, melanin
  • Cosmetic devices: Microneedles, patches, blue light
  • Penetration of active molecules or nanoparticles
  • Surface deposits

Skin knowledge

(Raman, AFM, SPRi, Fluorescence)

  • Impact of external factors: Pollution, UV
  • Chrono-photo-aging, hydration
  • Cell models, reconstructed skin, explants
  • Biofilms, lipidic films
  • Surface properties: Roughness, adhesion, molecular composition, coatings

Hair chemistry

(Raman, AFM, ICP, Fluorescence)

  • Effect of treatments: coloring, shampoos, masks and oils
  • Impact of routines: ironing, chemical straightening, bleaching
  • Environmental factors: humidity, sun exposure, ozone, metal content
  • Hair chemistry: keratin, sebum, melanin, water
  • Active penetration: cuticle, cortex, medulla
  • Surface functionalization and coatings

Raw materials

(Raman, AFM, ICP, PCA, XRF, Fluorescence)

  • Size distribution and zeta potential
  • Molecular and elemental composition
  • Quality control: Adulteration, origin, impurities, active molecule concentration, REACH
  • For small molecules, nanoparticles, polymers, lipids, proteins

Formulation

(Raman, AFM, PCA, SPRi, XRF, Fluorescence)

  • Spreading, film homogeneity
  • Size of domains, particles spatial distribution
  • Interaction with packaging, stability
  • Micro-nanoemulsions, micelles
  • Encapsulation and loading with delivery systems: Liposomes, capsules, microspheres

Back to top.

HORIBA Solutions

The cosmetics industry requires intricate analytical solutions for evaluating product safety, efficacy, and quality, and to deliver reliable, compliant, and effective formulations.

Our advanced instruments are designed to furnish essential insights for making informed decisions about the quality and performance of cosmetic products. Tailored to meet the distinctive requirements of the cosmetics industry, our solutions cover a range of needs, from raw material selection and characterization to product formulation and development. Additionally, they offer valuable information on skin and hair knowledge, enhancing our understanding of their structures and specific needs.

LabRAM Soleil

Raman imaging faster than before to support your ingredient selection and skin & hair care formulation development to achieve desired effects and product performance.

Duetta

Fluorescence A-TEEM replaces your HPLC workflow for qualification of raw materials by a rapid optical fingerprinting control.

nanoGPS tag

nanoGPS navYX for direct and fast relocalization between different imaging modalities (Raman, μFTIR, SEM…), thus complementing nanoscale observation with chemical characterization.

SmartSPM

Atomic Force Microscopy (AFM) finally made easy for all, with the bonus of added chemical capabilities on the same spot, for your routine work at the nanoscale.

XGT-9000

Micro-XRF measures elemental quantities, even at the microscopic particle level, and identifies the presence of contaminants. Through mapping analysis, it details the distribution of elements in formulation spreadings.

Partica LA-960V2

Foundations, sunscreens, eye shadows or creams include particulates (pigments, exfoliants, mineral powders…) or appear in the form of emulsions. Their size distribution, as raw materials or formulated, is obtained with laser diffraction analyzers.

OpenPleX

SPRi studies can benefit cosmetics research by guiding the formulation optimization process, through the understanding of binding affinity, pharmacokinetics, and the dose-response relationship between an active molecule and its target, to finetune ingredient concentrations.

ULTIMA Expert

ICP-OES quantifies metallic traces (Ti, Fe, Zn, Al…) at low concentrations in raw materials, packaging or biological matrices like hair or nails, for performance and safety evaluation (Pb, Hg, Cd, Co…)

nanoPartica SZ-100V2

Dynamic Light Scattering (DLS) brings, in addition to particle size determination, the Zeta Potential to support the development of stable suspensions or emulsions, predicts interactions, and optimizes the formation of films and coatings.

Raman with EDF and HSI

Cytoviva modules (Enhanced Dark Field and Hyperspectral imaging) can be integrated onto a Raman imaging platform. This allows capturing very large area HSI and EDF images with high spatial and spectral resolution. Nanoparticles can be easily Raman detected on skin, hair or formulations.

Back to top.

Application notes

Pharmaceutical compounds distribution and cosmetic products analysis

In the final step of the formulation process, pharmaceutical and cosmetic industries have to control their products to check if the compounds' distribution in the final product, or in its application form, i.e. dispersed on a skin for an intracutaneous product, are homogenous and stable in order to guarantee the product's efficacy.

Particle Size Determination of Mineral-Based Sunscreens

The safety and effectiveness of zinc oxide is size dependent. It is important to monitor the particle size of both active and inactive ingredients of sunscreen to maintain its intended efficacy and safety, while preventing the active ingredient from penetrating deep into the skin.

Endogenous Skin Fluorescence In Vivo on Human Skin

The fluorescence spectra of intrinsic protein fluorophores have been studied extensively and used in investigating biological events.

Related application notes

相关应用

Back to top.

FAQ and users' papers

FAQ

Explore our FAQ dedicated to advanced analytical solutions for comprehensive cosmetic products characterization

Users' papers

Discover how our instruments help research teams in solving their development problematics

Back to top.

Downloads

 ↑ 回到顶部

留言咨询

如您有任何疑问,请在此留下详细需求信息,我们将竭诚为您服务。

* 这些字段为必填项。

Corporate