Pentra C400

HORIBA Medical Clinical Chemistry Analysis Pentra C400

From routine to specific tests, perform them all on a single system.

 General Description

  • Analysis Method Types:
    • Spectrophotometry: Colorimetry and Turbidimetry
    • Potentiometry: Direct (Serum or Plasma) and Indirect (Urine)
  • Up to 55 assays on board
  • Optional ISE Module (Na+, K+, Cl-)
  • Maximum Throughput: 420 test/h
  • CE Marked

Sample Handling

  • Sample Capacity: 6 racks with 10 sample positions for primary tubes or cups
  • Continuous loading
  • Positive Sample Identification: Integrated Barcode Reader and Tube Presence Detector
  • Sample Integrity:Level, Shock and Clot Detection
  • Sample Collection Format: 0.7, 4, 5, 7 and 10 mL (diameter: 16mm)
  • Sample Specimen: Serum, Plasma, Urine, CSF, Whole Blood, Homogeneous Fluids
  • Sample Volume: 2 to 380 µL
  • Automatic Sample Dilution: from 1/2 to 1/22,500
  • ISE: 20 µL (Indirect) or 60 µL (Direct)
  • Automatic Post Concentration: from x2.0 to x 10.0
  • Automatic Re-run

Calibrator/Control Handling

  • Calibrator/Controls Positioning on Sample or Reagent Tray
  • Automatic Standard Dilution Series:
    • Dilution Factors: Main Direct 1/2 - 1/150
    • Dilution Factors: Main Indirect 1/2 - 1/1508

Reagent Handling

  • 52 Reagent positions on board:
    • 44 in a closed refrigerated area (2-10°C)
    • 8 at room temperature
  • Positive Reagent Identification:Integrated Barcode Reader
  • Reagent Probe : Level Detection and Preheating
  • Reagent Management with Cassettes: Automated Reagent On-board Stability Check plus Test Countdown with automatic back-up
  • Reagent Volume: from 2 to 600 µL

Reaction System

  • Reaction Volume: 150 to 600 µL
  • Reaction Temperature: Air bath at 37°C
  • Photometer Reaction Cycle:12 seconds
  • Mixing with Teflon-coated Stirrer
  • Reaction Time:  1 to 100 cycles
  • Disposable Acrylic Cuvettes
  • Automatic Cuvette Changer
  • Cuvette Capacity:  36 segments (432 cuvettes)
  • 7 Integrated Calculation Algorithms


Pentra C400 Video (click here)

Segment: Medical
Manufacturing Company: HORIBA ABX SAS
Base product: Pentra C Series
  • 55 on-board assays
  • Innovative cassette format
  • Integrated work station and validation station
  • Touch screen
  • Real-time viewing of your workflow


System Size40” x 28” x 25” (W x L x H)
System Weight264 lbs
External Cooling Unit Size12” x 17” x 16” (W x L x H)
External Cooling Unit Weight77 lbs
Sound level< 60 dBa
Operating temperaturefrom 15 to 32°C
Operating Humidityfrom 20 to 85%
Total Power Requirements (with Printer)1000 VA
WaterDe-ionized/Distilled Water - 10L Tank
Water specifications 
  • Resistivity > 5 MegOhms
  • Conductivity < 0.2 µS/cm


Computer & Software

Operating systemWindows XP
Data processing 
  • 12 inch Color LCD Touch Screen
  • Database Capacity: 100,000 results
  • Processor: 600 MHz
  • RC 232C: Patient results, QC to LIS with ASTM protocol
Integrated Validation Station
Quality Control ManagementLevey Jennings, Automatic QC, Default controls and Westgard rules
  • Reagents, Quality Control, Calibrations
  • Applications, Maintenance, Sequencing, Flags and Alarms
Export of archived data and Quality Control data (QCP)USB key
Audible alarms 
Interactive HelpHTML Format


Optical System

Tungsten-halogen Lamp
Measurement Principle 
  • Bi-chromatic light absorbance
  • Choice of 15 wavelengths from 340 to 700 nm
  • Wavelength selection with holographic grating technology
SensorPhoto diode array
Optical Linearity2.5 A. at 340mm; 3.0 at other wavelengths
Organ function & metabolism control
Organ function & metabolism control
Clinical Chemistry can measure the blood levels of many proteins, enzymes, ions. These blood levels are related to the activities of many organs and to the general metabolism of the patients. The functions of organs thus explored, are essentially related to the hepatic, pancreatic, renal, muscular or even cardiac functions.
Abnormal metabolism diagnosis
Abnormal metabolism diagnosis
The clinical chemistry dosages of proteins, enzymes and ions, provide the measurement of concentrations for all of these analytes. When these measurements reveal blood molecular concentrations outside normal values, the interpretation of the results may lead to the diagnosis of pathological metabolism.
Disease & metabolism monitoring
Disease & metabolism monitoring
Clinical chemistry instruments allow the monitoring of certain diseases, just as they allow the monitoring of specific molecules or drugs.
Drugs detection
Drugs detection
A particular application in clinical, chemistry that allows the detection of illicit, natural or synthetic products. It's about detecting the abnormal presence in the urine or in the blood of drugs of abuse.

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