PSA300

PSA-300 image

Static Image Analysis System Particle Size

The HORIBA PSA 300 is a state of the art turn-key image analysis solution. Seamless integration of Clemex's powerful particle characterization software and an automated microscope with high resolution camera creates an intuitive, easy-to-use imaging workstation. Addressing a need in the field of particle characterization, the PSA 300 is a versatile particle size and particle shape analysis tool that can be used in a wide range of applications in the pharmaceutical industries and material science. It is a turnkey solution for labs that want to maintain an analytical microscopy environment with minimum intervention by the operator yet still yield maximum detail in the results.

 

Segment: Scientific
Division: Particle Characterization
Base product
  • Particle shape information-  Industry experts, especially pharmaceutical, are now looking to characterize particle shape in addition to particle size, to gain a better understanding of how shape can effect the various properties of a product. More are recognizing the significance of particle size and shape as well as their impact on the physical characteristics of many particulate materials. Process problems with drug substances can often be attributed to the particle size or shape of the active material.
  • Sensitivity and accuracy - PSA300 features excellent resolution and detection of micronized particles as small as 0.5 microns. Our unique automated calibration routine assures complete validation of measurement accuracy in accordance with NIST standards. Particle volume determination is based on absolute 2D measurements and thus not limited to spheroids. Accurate volume measurements can be performed on elongated cylinders, acicular or irregular shaped objects.
  • Repeatability - Microscope parameters and camera settings are saved as properties in the routine associated with each sample. In conjunction with an automated workstation, an image analysis routine can be executed multiple times with no deviation from the initial results. This guarantees reproducibility and traceability of analysis, ensuring accurate results and conforming to 21 CFR Part 11 requirements.
  • High Throughput - Data collection is achieved through multiple field analysis using a Clemex 4-slide sample holder and motorized stage. Our robotic image analysis system will allow the user to measure large number of slides simultaneously without any operator intervention.
  • Results Management - PSA300 automatically calculates various measurements simultaneously on thousands of individual particles. It is capable of generating statistically significant results in an amazingly short time. The powerful report generator allows speedy data processing and flexible reporting capabilities.
  • Security and Compliance - PSA300 allows the management of user rights, audit trail of critical interventions, electronic signatures as well as overwrite protection of all electronic documents produced by PSA300 imaging workstation (images, stage patterns, image analysis routines, raw binary data, image analysis report in PDF). Traceability is assured by saving all analysis settings, data, results, and images (if required) in the same protected file. All of these security features are designed to conform to regulatory requirements such as FDA 21 CFR part 11 ensuring data integrity.

 

 

  • Size range: 0.5-1000 µm
  • Objectives: 2.5X, 5X, 10X, 20X and 50X.
  • Automation: Computer controlled Motorized nosepiece, Computer controlled Motorized condenser, Computer controlled Motorized focus, 0.05mic/step, Motorized stage 215 x 75 mm travel, 0.5 mic/step, CLEMEX Motorized stage controller assembly.
  • Measurement time: Between 2 and 30 minutes depending on particle size and number of particles analyzed.

Principle of Operation

The use of automated image analysis is increasingly being recognized as an attractive technique to characterize particle shape and size distribution. Traditional methods, such as laser diffraction, although highly efficient, give limited information on particle shape proving image analysis as the best tool for performing particle analysis.

 

Accessories

Disperser Unit –  An automated sample disperser subjects powder samples to a controlled quantity of force by subjecting the sample to a burst of air as a vacuum is released. The sample disperser breaks agglomerates and assures an even spread of sample across the slide. Unit includes disperser column, two slides base, high vacuum dry pump assembly, and USB computer control unit and software.

PSA Guidebook
CategoryDocuments
Size 1.81 MB
FiletypePDF
PSA300_2018
CategoryDocuments
Size 4.7 MB
FiletypePDF
Overview
CategoryDocuments
Size 0.84 MB
FiletypePDF

REQUEST FOR INFORMATION

Do you have any questions or requests? Use this form to contact our specialists.

Related products

3D Surface and Volume Display
More3D Surface and Volume Display
3D confocal volume control and display
AFM-Raman - TERS Probes
MoreAFM-Raman - TERS Probes
Reliable, efficient TERS probes for NanoRaman imaging
APDA-372
MoreAPDA-372
Ambient Dust Monitor
APMC-370
MoreAPMC-370
Air Pollution Multigas Calibrator
Auto SE Accessories
MoreAuto SE Accessories
Customize your instrument
Auto Soft
MoreAuto Soft
Intuitive Auto-Soft Interface for the Auto SE and Smart SE
Batch Processing
MoreBatch Processing
High throughput data processing
CaptuR – Laser Trapping Solution - Raman Accessory
MoreCaptuR – Laser Trapping Solution - Raman Accessory
Raman Accessory for Life Science
Cathodoluminescence F-CLUE
MoreCathodoluminescence F-CLUE
Compact Hyperspectral CL
Cathodoluminescence H-CLUE
MoreCathodoluminescence H-CLUE
Versatile Hyperspectral CL
Cathodoluminescence i-CLUE
MoreCathodoluminescence i-CLUE
Fast Imaging CL
Cathodoluminescence R-CLUE
MoreCathodoluminescence R-CLUE
Raman PL & CL
CC-55 Imaging Spectrometer
MoreCC-55 Imaging Spectrometer
Control unit PE-D20
MoreControl unit PE-D20
Conversion adapters CA series
MoreConversion adapters CA series
CP20 Series
MoreCP20 Series
OEM miniature spectrograph
CS-100F4
MoreCS-100F4
Multi-point Chemical Solution Monitor
Customize with VBS
MoreCustomize with VBS
Scripts and ActiveX
Customized reporting
MoreCustomized reporting
Create templates for fast data reports
Dedicated power sources PE Series
MoreDedicated power sources PE Series
DeltaPsi2 Software
MoreDeltaPsi2 Software
A Platform for HORIBA Scientific Ellipsometers
Detector - Hyperspectral camera and imaging sytems (HSI)
MoreDetector - Hyperspectral camera and imaging sytems (HSI)
Display unit DU series
MoreDisplay unit DU series
DuoScan™ Macro and Sub-Micron Raman Mapping
MoreDuoScan™ Macro and Sub-Micron Raman Mapping
Raman Accessory for fast imaging
Eco Web
MoreEco Web
Data Management and Reporting Software
EMIA-Step
MoreEMIA-Step
Carbon/Sulfur Analyzer
Environmental Raman Stages
MoreEnvironmental Raman Stages
Epifluorescence
MoreEpifluorescence
Cooled fluorescence imaging cameras
Ez suite
MoreEz suite
Powerful software suite for high-throughput label-free molecular interaction assays
EzSpec Software
MoreEzSpec Software
Fast Feed Back Auto Focus
MoreFast Feed Back Auto Focus
Raman Accessory for Imaging
Flat Correction
MoreFlat Correction
Unique fluorescence removal tool
GDOES Accessories
MoreGDOES Accessories
Accessories for samples with various shapes, sizes and properties
Gratings - OEM Diffraction Grating
MoreGratings - OEM Diffraction Grating
OEM gratings design and production capabilities
High Performance Detectors
MoreHigh Performance Detectors
ICP-OES
MoreICP-OES
Complete your ICP-OES Spectrometer for your specific needs
Image Analysis and Display
MoreImage Analysis and Display
Convert map data into chemical images
Instant Processing
MoreInstant Processing
On-the-fly custom data processing
IOX-370
MoreIOX-370
Datalogger IO-Expander
Labspec 6 Spectroscopy and imaging software
MoreLabspec 6 Spectroscopy and imaging software
LabSpec 6: Validated performance
MoreLabSpec 6: Validated performance
LabSpec 6 is a validated software
Mass Flow Checker MFT-20
MoreMass Flow Checker MFT-20
MESA-7220
MoreMESA-7220
Measurement of Sulfur and Chlorine in Petroleum Products
Microscope Objective UVI 74x
MoreMicroscope Objective UVI 74x
Mini CCT Plus
MoreMini CCT Plus
Mini Raman Spectrometer
Monitor unit PE-D10
MoreMonitor unit PE-D10
Motorized XY Mapping Stages
MoreMotorized XY Mapping Stages
Multivariate Analysis
MoreMultivariate Analysis
Data analysis for complex data sets
MultiWell Module
MoreMultiWell Module
NavMap Application
MoreNavMap Application
Lets you navigate easily through your image
NavSharp
MoreNavSharp
Navigate your sharp image in real-time
OEM Raman Lasers with wavelength-stabilization
MoreOEM Raman Lasers with wavelength-stabilization
Only available for volume OEM purchase, minimum order quantity 50 units.
OEM Raman Miniature Probes
MoreOEM Raman Miniature Probes
OEM Miniature Raman Systems and Components
OneCheck System Validation
MoreOneCheck System Validation
Alignment and calibration tools
OneClick
MoreOneClick
Fast and easy Raman acquisition
OZGU-370SE
MoreOZGU-370SE
Ozone Transferstandard
Particle Finder
MoreParticle Finder
PE-S7
MorePE-S7
PP-TOFMS Software
MorePP-TOFMS Software
Egonomic software for data acquisition, data treatment and technical support
ProtectionPlus Module
MoreProtectionPlus Module
Regulatory compliance and data integrity
CAMSIZER P4*
MoreCAMSIZER P4*
Dynamic Image Analysis System Particle Size
CAMSIZER X2*
MoreCAMSIZER X2*
Dynamic Image Analysis System Particle Size
Partica LA-960
MorePartica LA-960
Laser Scattering Particle Size Distribution Analyzer
Partica mini LA-350
MorePartica mini LA-350
Laser Scattering Particle Size Distribution Analyzer
PrintQuest
MorePrintQuest
Automated Fingerprint and Palmprint Identification - AFIS & APIS Systems
SZ-100
MoreSZ-100
Nanopartica Series Instruments
ViewSizer 3000*
MoreViewSizer 3000*
The Better Way to Characterize Nanoparticles
CAMSIZER P4*
MoreCAMSIZER P4*
Dynamic Image Analysis System Particle Size
CAMSIZER X2*
MoreCAMSIZER X2*
Dynamic Image Analysis System Particle Size
ViewSizer 3000*
MoreViewSizer 3000*
The Better Way to Characterize Nanoparticles