Sensor Chips for Label-Free Interaction Analysis

Sensor Chips for Label-Free Interaction Analysis

SPRi-Biochips™ and SPRi-Slides™ are designed exclusively for HORIBA SPR imaging instruments. The flexible configuration of the spot matrix is suitable for the analysis of hundreds of molecular interactions in parallel.

Segment: Scientific
Division: Molecular and Microanalysis
Base product

SPRi-Biochips™ and SPRi-Slides™ are designed exclusively for HORIBA SPR imaging instruments. The sensor chips are made of a high refractive index glass prism coated with a gold thin film specially developed for imaging purposes. Importantly, the sensor chips can be provided with pre-functionalized surface chemistry or as bare biochips suitable for exploring your own chemistry and target molecule detection.

To detect biomolecular interactions, ligands are first grafted (spotted) onto the sensor chip surface. Depending on the diameter of the spots, up to 400 spots (150µm) or 64 spots (500µm) can be deposited on the 1cm2 sensitive surface of the biochip.

With the appropriate regeneration procedure, spotted SPRi-Biochips™ are re-usable at least 100 times saving on consumable costs.

Ligands can be spotted manually or using commercially available spotting systems (SPRi-Arrayer and SPRi-CFM) for more demanding applications.

 

Unfunctionalized surfaces

Au-coated biochips are available to allow for your own surface chemistry.

  Packages
SPRi-BiochipPrism with a thin gold layer5 units
SPRi-SlideSlide with a thin gold layer10 units
PrismHigh index glass prism2 units
Etched prismHigh index glass prism with an etched surface1 unit
Index matching liquidHigh index liquid for connection between glass prism and SPRi-slides1mL

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