Biopharma and Pharma

Cell Culture

Spectroscopy offers valuable insights into cell health, growth, and product production. Bioluminescence assays measure ATP levels, providing a direct measure of cell viability and energy production. Flow cytometry and automated cell counters use light scattering to count cells and measure their size, providing information on cell growth and proliferation. HORIBA is currently using the ATEEM Fluorescence technology via the Aqualog, to monitor cell culture quality and to ensure that some of the components that are less sensitive to traditional in-line techniques are present in sufficient concentration for optimal cell growth. 

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Browse Application Notes

Medical gases are regulated by the United States Pharmacopoeia (USP), European Pharmacopoeia (EP) and Japanese Pharmacopoeia (JP) that sets standards for all medical gases including those that address quality, strength, purity, packaging, labeling, and identification. HORIBA contributes in this field by providing a wide range of analysis and measurement solutions with high accuracy.

Monitoring Cell Culture Media Variability using A-TEEM Spectroscopy

Cell culture media for bioreactors are usually prepared as an aqueous solution and provide everything a cell line needs for optimal growth as well as product yield and quality. Even subtle variations in composition could have a noticeable impact on the growth rate of the cell culture and its yield. Thus identifying and analyzing cell culture media is important.

Holistic Analysis of Mammalian Cell Proliferation using Fluorescence Spectroscopy

Monitoring culture media conditions is highly important for industries in order to improve cell proliferation for applications such as regenerative medicines and protein synthesis.

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Explore our Products

XploRA™ PLUS

MicroRaman Spectrometer - Confocal Raman Microscope

Aqualog - A-TEEM Industrial QC/QA Analyzer

Aqualog - A-TEEM Industrial QC/QA Analyzer

A Simple, Fast, “Column Free” Molecular Fingerprinting Technology

ViewSizer 3000

Simultaneous Multi-Laser Nanoparticle Tracking Analysis (NTA)

Duetta

Fluorescence and Absorbance Spectrometer

MacroRAM™

Affordable Benchtop Raman Spectrometer

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Watch Webinars and Videos

The A-TEEM Compliance Package is now available from HORIBA and enables A-TEEM to be used in a GMP environment. Discussion points will be around both the pharmaceutical applications of A-TEEM and the details of the compliance package for GMP labs.

Join Dr. Kevin Dahl of Particlese LLC and Dr. Linda Kidder of HORIBA Scientific provide tips and alternative solutions for better vaccine development and quality. They will discuss the application of multi-laser nanoparticle analysis (NTA) in determining vaccine degradation and total particle count. They will also present a new analytical approach, fluorescence A-TEEM method for rapid screening of similar but different vaccine final formulations.

The large variety of fluorescent probes, such as organic dyes, biological biotags and fluorescent nanostructures, are intensively studied due to their inherent suitability for a wide range of life science applications. Thanks to the complementary nature of its analytical solutions, HORIBA's unique offer covers fluorescence, particle analysis, AFM, Raman and XRF characterization techniques, helping to gain valuable insight into optical properties, size, morphology and composition of your bioprobes.

New camera, new imaging, new FLIM

Fast auto sampling. Auto fast sampling. Auto sampling, fast

Quantitative imaging techniques, such as FRET-FLIM, FCS and FCCS, and RICS are powerful tools to monitor the dynamics and interactions of proteins in live cells.

The need for fluorescent bioprobes has exploded in the last decades in the Life Sciences and Medical domains for applications such as bioimaging, lab-on-chip diagnostics, drug development or cell sorting.

A-TEEM™ stands for simultaneous Absorbance, Transmission, and Fluorescence Excitation-Emission-Matrix (EEMs) Acquisition.

Byron Purse on his work modifying Fluorescence of DNA & RNA

The simple and ideal excitation sources for TCSPC

EzSpec Software for Duetta and its winning user experience

Money down on this Head 2 Head EEM acquisition comparison

A-TEEM acquires chemical ID with fluorescence spectroscopy

Automatically discover Fluorescence profiles in about 60 seconds

EzSpec and its apps, making research too EZ

One of those things that make EzSpec so good

Automatically discover Fluorescence profiles in about 60 seconds

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