Analytical Chemistry in Pharmaceuticals and Medicine Manufacturing
XGT-9000
X-ray Analytical Microscope
The evolution of μXRF! Combination of improved sensitivity and new imaging technology achieved high speed analysis of foreign materials in only one unit.
- Simple analysis operation with no preparation required and non-destructive analysis.
- Measurement points can be accessed quickly through high-precision optical observation, even in the microscopic range.
- Complete with a variety of image analysis software.
Clear and High-speed Image Mapping
- Shortened analysis time facilitates efficient measurement work.
- X-ray images with very little noise allow for even clearer observation.
Clear Optical Image Observation and Coaxial X-ray Irradiation
- Equipped with three kinds of illumination: coaxial, around and transmitted. Combining coaxial and around illuminations enables clear observation of samples with areas that are uneven, mirrored, etc.
- Coaxial, perpendicular X-ray exposure and optical image observation prevent the measurement position of samples from becoming misaligned.
Employing of imaging technology based on Raman imaging technique
Highlighting a certain element as a characteristic point simplifies detection of foreign material, obstacles, etc.
A New Solution in Foreign Material Analysis
Foreign material is detected quickly through high-speed screening and highlighting through imaging processing. Additionally, the high resolution X-ray beam enables detailed analysis of elements contained in foreign material. This series of foreign material analyses can be completed with a single unit, up to the level of several ten μm.
Applications
■ Analysis of Foreign Material in Films
Even difficult to visually confirm foreign materials can be detected and analyzed while checking optical observation images with high resolution of them after elemental mapping screening.
■ Analysis of Hydrous Samples
Enables measurement of hydrous samples and foreign materials can be detected through image processing.
| Model | XGT-9000 | XGT-9000SL |
|---|---|---|
| Basic information | ||
| Instrument | X-ray fluorescence analytical microscope | |
| Sample type | Solids, Liquids, Particles | |
| Detectable elements | F － Am | |
| Chamber size | 450(W) x 500(D) x 80(H) | 1030(W) x 950(D) x 500(H) |
| Maximum sample size | 300(W) x 250(D) x 80(H) | 500(W) x 500(D) x 500(H) |
| Maximum mass of sample | 1 kg | 10 kg |
| Optical observation | Two high resolution cameras with objective lens | |
| Optical design | Vertical-Coaxial X-ray and Optical observation | |
| Sample illumination/observation | Top, Bottom, Side illuminations/Bright and Dark fields | |
| X-ray tube | ||
| Power | 50 W | |
| Voltage | Up to 50 kV | |
| Current | Up to 1 mA | |
| Target material | Rh | |
| X-ray optics | ||
| Number of probes | Up to 4 | |
| Primary X-ray filters for spectrum optimization | 5 positions | |
| Detectors | ||
| X-ray Fluorescence detector | Silicon Drift Detector (SDD) | |
| Transmission detector | NaI(Tl) | |
| Mapping analysis | ||
| Mapping area | 100 mm x 100 mm | 350 mm x 350 mm |
| Step size | 2 mm | 4 mm |
| Operating mode | ||
| Sample environment | Full vacuum / Partial vacuum / Ambient condition | Partial vacuum / Ambient condition* * Detectable elements for SL version are from Na to Am |
Dimensions (unit: mm)
Battery Evaluation in Electrical Equipment
Analytical Chemistry in Chemicals
Analytical Chemistry in Electrical Equipment
Micro-XRF for non destructive analysis of museum and archaeological objects
The XGT-5000 is ideally suited for analysis of archaeology specimens and museum objects.
Analysis of a coloured illustration in a Nepalese manuscript was carried out to understand more fully the types of pigments used to obtain particular hues. Due to the penetrating nature of x-rays it was possible to probe not only the topmost layer of pigments, but also those which had been used for undercoating.
Biological applications of XRF microscopy
X-ray fluorescence (XRF) micro-analysis provides the research with a fast and non-destructive means of measuring elemental composition on a microscopic scale. However, it has long been a drawback of the technique that analysis must be carried out under vacuum conditions. Whilst for many applications this presents no problem other than inconvenience and time, within biological fields it means that many desired experiments are simply not possible. The vacuum conditions will quickly dehydrate and damage the typical water containing samples (leaves, micro-organisms, tissue, cells etc) key to biological/medical research. However, the unique x-ray guide tube technology of the XGT-5000 now allows high spatial resolution analysis for all elements from sodium (Na) to uranium (U) at atmospheric pressure – hence, hydrated samples, fine powders, and even liquids, can now be safely analysed for composition (quantitative and qualitative) and element distribution.
Elemental micro-analysis of leaves using EDXRF
X-ray fluorescence (XRF) provides fast characterisation of sample element composition down to parts per million (ppm) levels – however, biologists often ignore this useful technique because it traditionally requires destructive vacuum conditions. Bio-samples containing large amounts of water will quickly dehydrate under these conditions. With the groundbreaking XGT-5000, though, these concerns are removed. Samples are analysed at normal atmospheric pressure, so that the resulting qualitative/quantitative data truly represents a healthy sample. In this application note the unique 10 µm spatial resolution of the XGT-5000 coupled with atmospheric pressure analysis allows leaf structure and behaviour to be explored. By using a combination of single point analysis and mapped imaging it is possible to learn more about the growth of leaves, and their behaviour in the presence of pollutants.
Elemental analysis of single rice grains using XRF micro-analysis
Rice is an important food source for humans, and represents the principal food source for over half the world population. It is native to south-east Asia, and has been cultured for over 7,000 years. In this application note, individual rice grains are investigated using the XGT-5000 x-ray fluorescence microanalyser, providing insight into the elemental changes occurring during rice processing.
