We all consume or have all consumed sugary drinks at least once. Sugar content of those drinks must be regulated. Also, to avoid those properties of sugar, it has been replaced by sweeteners. These have lower sweetness than natural sugars. Whether it is sugar or sweetener, their content just be controlled. Here, we demonstrate that Raman spectroscopy is one solution to identify and evaluate sugar/sweetener concentrations in a quality control process.

Disinfecting your hands with hydroalcoholic gel has become a daily practice. In the meanwhile, 70° alcohol has been used for even longer to disinfect wounds. But, to remain efficient, the alcohol concentration of these products must not be below a defined threshold and must be controlled. This application note demonstrates how to evaluate alcohol concentrations in a quality control process with Raman.

Optical microscopy is very common technique for visualization and characterization at the micron scale. Many modalities exist to highlight different features. However, the chemical information is almost always missing missing. Raman spectroscopy is a complementary technique that can provide chemical information about the sample.
During this webinar, we will present how these different microscopy modalities, combined with Raman spectroscopy, make Raman microscopy so powerful.

Raman microscopy is couples both submicron-scale spatial resolution and high spectral resolution. Thus, achieving the best performances is dependent on a good calibration in both spatial and spectral dimensions.
During this webinar, we will detail the different calibration routines applied on Raman microscopy to achieve ideal measurements while remaining compliant with regulations. We will also explain how these routines work and why they are important to consider.

Raman microscopy is more and more becoming a standard method in many application domains. This transforms Raman microscopy from a high-end technique to one that is widely used. Consequently, it has to come with tips-and-tricks, but also with dedicated tools to support these different applications. These supporting tools can be accessories or software dedicated apps.
During this webinar, we will detail the tools and accessories supporting Raman microscopy for specific applications.

Multilayer polymer films, composed of different materials, are used in a variety of industrial applications. The analysis of these multilayers is important to support, especially for safety and performances control. Here, we use Raman microscopy by cross-section analysis and confocal depth profiling to investigate the chemical composition of two multilayers films.

In this study we have chosen to investigate pyrite and its surrounding minerals in order to identify the different mineral phases as well as the chemical variations from micro- to nano-scale. Using the different microscopes instruments and being co-localized allows a comprehensive characterization of the sample and a precise superimposition of all the images.

In recent years, core-shell particles have attracted significant attention due to their smart properties. Size, morphology, and composition are the key features that strongly affect the performance and suitable applications of such structures.

The International Conference on Advanced Applied Raman Spectroscopy (RamanFest2022) will feature presentations from world-leading Raman experts and researchers using the technique across varied applications within life science, materials science, and energy and environmental analysis. It will bring together the world's Raman community to share, learn and discuss how Raman spectroscopy is being applied to today's problems and pioneering tomorrow's capabilities.

Confocality is one important feature of HORIBA Raman microscopes. Confocal is defined as having the same focus or foci, and in the context of optical microscopy, a confocal microscope is one with an aperture (called a confocal hole) in a conjugate focal plane, whose imaging system only collects light from the sample focal plane, giving greater spatial resolution.

With SmartSampling^™ discover a revolutionary mapping approach for samples unsuitable for ultra-fast scanning methods which rely on high signal and high laser powers. Using an advanced image compression algorithm, HORIBA's patented technology results in high spatial resolution Raman images with all the detail acquired in a fraction of the time. Its non-linear mapping motion gets the detail quickly, focusing on what matters, and ignoring what doesn’t.

SmartSampling point-by-point mapping runs up to a 100 times faster, without losing the detail. You have to see this to believe it.

Get expert level images with just one click. EasyImage is more than a software function, it is your new laboratory partner. Just focus on your sample, then EasyImage will optimize the image acquisition parameters. If you only want to map a specific area, no problem. Simply select it on the video image, obtain a preview and then get your Raman image with chemical characterization

Raman microscopy is one of the most powerful techniques to analyze and characterize even the smallest microplastic particle. Therefore, it becomes an invaluable technique in understandingthe origin of contaminants and their consequences on environment and health.

In addition to offering powerful Raman Microscopes, i.e. LabRAM Soleil™ and XploRA PLUS, HORIBA provides a full analysis solution for microplastics, ranging from sample preparation, through data acquisition down to data treatment and reporting for a complete morphological and chemical characterization of microplastics.

Due to Covid-19, a wide choice of protective masks are now on the market. These types of masks are distinguished, in particular, by their different efficiencies linked to their filtration capacity. These differences in protective properties have therefore made it essential to characterize the composition of the masks. In this paper, we present why LabRAM Soleil™ confocal Raman multimode microscope is the perfect tool for studying the distribution and composition of mask fibers.

An imaging platform that combines Raman microscopy with enhanced darkfield and hyperspectral imaging technology was used to study lung tissue sections containing carbon nanotubes. It enabled easy identification of the regions containing the carbon nanotubes followed by spectroscopic characterization of chemical composition.

Your ideal lab companion

The result of 50 years of expertise in Raman spectroscopy, LabRAM Soleil™ offers unprecedented capabilities for Raman multimodal confocal imaging, in a compact footprint.

Due to the high level of automation implemented, high optical throughput, objective recognition, motorized switching mirrors, ultra-fast mapping capabilities with SmartSampling™ and QScan™, fast motorized 4-grating turret, high speed auto-alignment and new options offered by the LabSpec 6 software suite, the LabRAM Soleil™ is ready to work 24 hours a day with minimal human supervision.

HORIBA Raman confocal microscopes use a variety of research grade upright, open space and inverted microscopes from different vendors, including Olympus and Nikon. This technical note describes the available options and explains their typical use, assisting the selection of relevant options at the time of order or for future upgrade.

In order to overcome limitations in spectral range offered by standard dielectric mirrors, HORIBA developed a customized dielectric mirror for the LabRAM Soleil™, the new Confocal Raman Multimode Microscope.

Discover more unique features of LabRAM Soleil™

In this article, we present how our Raman and X-Ray Fluorescence microscopies can be combined to shed some light on the origins of the universe. We show some examples on a meteorite piece and on water inclusion in quartz matrix.

QScan™, a patented unique feature of LabRAM Soleil™, generates highly homogeneous laser lightsheet, enabling non-destructive confocal slicing of multilayer samples. It enables mapping without moving and true point-and-shoot operation, when one can directly acquire a spectrum by clicking anywhere in the video image.

Discover more unique features of LabRAM Soleil™

Spectral resolution is one of the most important factors to think about when acquiring a Raman spectrum. Defined as the wavenumber, wavelength, or frequency difference
of two still distinguishable lines in a spectrum, spectral resolution requirements vary depending on the information one would like to obtain.

Segmented channel waveguides have been fabricated in single crystal KTiOPO4 through a topotactic process of partial cation exchange. The ion-exchanged waveguides maintain the high nonlinear susceptibility of KTiOPO4 to function as frequency doubling laser light sources. We apply three dimensional (3D) Raman imaging to understand and characterize the changes to the chemical bonding and crystalline structure as well as measure the volumetric structure of the waveguide segments.