Top 10 Practices for ELS Zeta Potential

  1. Ensuring glassware is free of surfactants, soaps, and oils.
  2. Confirming repeatability of zeta potential measurements.
  3. Ensuring that you understand what ions are in your suspension.
  4. Ensuring that you know what surfactants and dispersing agents are in your suspension. 
  5. Measuring zeta potential as a function of suspension conditions such as pH or ion concentration.
  6. Increasing ion concentrations by decades (e.g., 1, 10, 100, …) rather than linearly (e.g., 1, 2, 3, …) when studying ion concentration effects.
  7. Ensuring that particle surfaces are fully wetted.
  8. Ensuring that the sample has reached thermal equilibrium with the sample chamber in the instrument so that the correct viscosity is used for zeta calculations.
  9. Remaining aware of the effect of atmospheric CO2 and its ions.
  10. Using background electrolyte when appropriate. 

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SZ-100 Nanopartica Series Instruments