Fluorescence

Fluorescence Spectroscopy for Cosmetics Research and Formulation

The development of innovative, high-performance cosmetic products relies on a rigorous understanding of complex biological matrices, such as skin, hair, and teeth, alongside the precise evaluation of active ingredients and formulation stability. Integral to this scientific oversight is fluorescence spectroscopy, a highly sensitive and non-destructive technique essential for tracking the ex-vivo and in-vivo penetration of topical actives, analyzing endogenous skin biomarkers, and assessing cellular damage caused by environmental stressors like UV exposure, blue light, and pollution. By delivering unprecedented sensitivity and molecular-level insights, HORIBA’s advanced fluorescence instrumentation allows cosmetic scientists to objectively validate product efficacy, optimize delivery systems, and ensure consumer safety.

Why use fluorescence in COSMETICS? 

  • Cosmetic products are made with chemicals that affect skin 
  • Many skin components fluoresce (protein, collagen, melanocites, NADH) 
  • Fluorescence can measure performance of cosmetics 
  • Skin aging and quality

 

What techniques are used to measure COSMETICS with fluorescence 

  • EEMs 
  • Synchronous scans 
  • Fluorescence microscopy 

 

Why use a HORIBA fluorometer in COSMETICS??  

  • High stray light rejection 
  • A-TEEM technology 
  • Direct fiber in-vivo measurements 

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