Yung Doug Suh, Ph.D., Principal Research Scientist, Director of Research Center for Convergence Nanotechnology
Address: Lab. for Adv. Molecular Probing (LAMP), Research Center for Convergence Nanotechnology, Korea Research Inst. of Chem. Tech. (KRICT), P.O. Box 107, Sinseongno 19, YuSeong-Gu, DaeJeon, 305-600, Korea

Academic background:

  • 1991, B.S. Chemistry
  • 1993, M.S. Physical Chemistry
  • 1999, Ph.D. in Nano Physics (Prof. Y. Kuk) and Physical Chemistry (Dr. D. Kim, Prof. S.K. Kim), Seoul National University
  • 1999-2000, PostDoc in Nano Spectroscopy, ETH Zurich, Swizterland

Professional career:

  • 2008,Visiting Scholar, NSEC/ Dept. of Physics, Columbia University, NY
  • 2005-2006 , Visiting Scholar, Dept. of Physics, Univ. Illinois at Urbana-Champaign, IL
  • 2003,Pres.  (Recruited) Principal Research Scientist & Founder of LAMP, KRICT
  • 2002-2003,Chief Scientist/RI&P Director, Nanohybrid Ltd. Inc.
  • 2001-2002,LTE Staff Member, Single Molecule Spectroscopy Lab., Environmental Molecular Science Lab (EMSL);Pacific Northwest National Laboratory of DOE/Battelle, WA (PNNL)  
  • 2000-2001/Assistant Professor (Res.), Dept. of Chemistry, Pohang University of Science and Technology (POSTECH)

Representative publications: (SCI & Scopus)

  1. "Observation of Fluorescence Emission from Solutions of C60 and C70 and Measurement of Their Excited-State Lifetimes",  J. Am. Chem. Soc. 114, 4429 (1992) cited > 180 times
  2. "Low-Lying Electronically Excited States of C60 and C70 and Measurement of Their Picosecond Transient Absorption in Solution", Chem. Phys. Lett. 196, 325 (1992) cited >100 times 
  3. "Stressed C60 Layers on Au(001)", Phys. Rev. Lett. 70, 1948 (1993) cited >130 times
  4. "Nanoscale Chemical Analysis by Tip-enhanced Raman Spectroscopy (TERS)", Chem. Phys. Lett. 318, 131 (2000) cited > 800 times.
  5. "Non-blinking and Non-bleaching Upconverting Nanoparticles as Optical Imaging Nanoprobe and T1 MRI Contrast Agent", Adv. Mater. 21, 4467 (2009), cited > 300 times. 
  6. "Nanogap-Engineerable, Raman-Active Nano-Dumbbells for Sing Molecule Detection", Nature Materials, 60, 90 (2010) cited > 400 times.
  7. "Highly uniform and reproducible surface-enhanced Raman scattering from DNA-tailorable nanopartciels with 1-nm interior gap", Nature Nanotechnology, 6, 452 (2011), cited > 220 times.
  8. "Long-term real-time tracking of Lanthanide ion doped upconverting nanoparticles in living cells", Angewandte Chemi, 50, 6093 (2011), cited > 80 times.


  • International invited talks in U.S. (Veeco, NIST x2, 2009 MSU, NSEC of Columbia U x2, 2013 LBNL Molecular Foundry, 2010 Rice U, 2012 MRS Spring, 2013 SPIE, 2013 Photonics West), Germany (2004 Max Plank Goettingen, 2004 ISAS Dortmund, 2012 U of Oldenburg), Swiss (Basel, Zurich), Spain (2012 NFO-12), Japan (Osaka, Handai, 2013 JASP-OSA Joint Symp. in Kyoto), Singapore (META 2014), and China (Yenji) including 1 plenary talk in the Netherlands (NFO-6) and 1 keynote speech (PIERS 2014).   
  • ISO Expert Member (TC201-SG9 SPM Division).
  • Nominated at Marquis’ Who’s Who, IBC, ABI since 2001.    • total citations: ~3100, h-index: 22, i10-index: 34
  • Program Committee of the 50th, 51st & 52nd SPIE Meeting, Nano Photonics Division.

Nanogap-Enhanced Raman Scattering (NERS) controlled by DNA

Since smSERS (single molecule Surface-Enhanced Raman Scattering) was independently reported by S. Nie group and K. Kneipp group in 1997 [1][2], tremendous amount of interest has been shown to this field because Raman spectroscopy can provide molecular fingerprint together with multiplexing capability in bioassay.  Regarding to the origin of this smSERS phenomena, so called “SERS hot spot”, Nie group argued sharp edges in nanostructure, such as corners of a silver nanorod or even of a single nanoparticle, can play as a hot spot of smSERS, while Kneipp group argued they could observe smSERS signal only from colloidal aggregation in solution.  Later on, Brus group and others showed that SERS hot spots, formed at the junction of two nanoparticles, likely play a major role in smSERS [3][4]. Theoretical calculations also support that SERS electromagnetic enhancement factors can approach up to ~1011 when inter-particle spacing reaches down to a few nanometer or less at the junction between two nanoparticle pair.  However, formation of these smSERS-active nanostructures with a nano-gap at the SERS hot-spot junction, mostly dimer or colloidal aggregation of Ag or Au nanoparticles adsorbed with Raman active molecules (e.g., Rhodamine 6G), is a random process driven by salt-induced non-specific aggregation. This fact has been a main hurdle for smSERS toward advanced applications.

Based on the idea that controlling this nano-gap between two noble metal nanoparticles is the key to realize reliable smSERS, we have designed a gold-silver nano dumbbell (GSND) and Gold Nanobridged Nanogap Particles (Au-NNP) to exhibit Nanogap-Enhanced Raman Scattering (NERS) controlled by DNA.  As for GSND, two gold nano particles with different sizes were linked to each other by double helix DNA (30mer), with a single Raman dye molecule at the center position, to fix the two at a known gap distance (~10 nm). Then we narrowed the gap down to < 1 nm by standard silver staining method to endow the GSND with single molecule sensitivity.  We have successfully detected smSERS signals, as well as typical single molecular blinking and polarization behaviors, from each GSNDs by Nano Raman spectroscopy at the single particle level [5]. As for Au-NNP, hollow spherical gap (~1 nm) between the gold core and gold shell can be precisely loaded with quantifiable amounts of Raman dyes labeled on DNA backbone which is anchored at the gold core and then covered by gold shell [6].

1. S. Nie and S.R. Emory, Science 275, 1102 (1997).
2. K. Kneipp, Y. Wang, H. Kneipp, L.T. Perelman, I. Itzkan, R.R. Dasari, and M.S. Feld, Phys. Rev. Lett. 78, 1667 (1997).
3. A.M. Michaels, M. Nirmal, and L.E. Brus, J. Am. Chem. Soc. 121, 9932 (1999).
4. Y.D. Suh, G.K. Schenter, L. Zhu, and H.P. Lu, Ultramicroscopy 97, 89 (2003).
5. D. Lim, K.-S. Jeon, H.M. Kim, J.-M. Nam, and Y.D. Suh, Nature Materials 9, 60 (2010)
6. D. Lim, K.-S. Jeon, J.H. Hwang, H.Y. Kim, S.H. Kwon, Y.D. Suh, and J.-M. Nam, Nature
Nanotechnology 6, 452 (2011).